Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.58 |
| ▸ | EED | O75530 | 1/20 | 0.46 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.46 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.46 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.46 |
| ▸ | EZH1 | Q92800 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12180716 | 0.85 | EZH2 (0.78) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2588199 | 0.79 | EZH2 (0.77) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2594868 | 0.77 | EZH2 (0.76) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2592844 | 0.76 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2588701 | 0.73 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2594829 | 0.71 | EZH2 (0.67) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2591172 | 0.69 | EZH2 (0.64) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2595098 | 0.69 | EZH2 (0.66) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL12180735 | 0.68 | EZH2 (0.61) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL2595322 | 0.68 | EZH2 (0.73) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566328-B1 | INDAZOLES | GLAXOSMITHKLINE LLC (US) | 2015-03-04 | — | — | EP | claimed |