⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702464 | 0.92 | — | — | |
| SCHEMBL31510311 | 0.89 | CA1 (0.52) | — | |
| SCHEMBL8676774 | 0.89 | CA1 (0.52) | — | |
| SCHEMBL31510310 | 0.89 | CA1 (0.52) | — | |
| SCHEMBL626215 | 0.81 | — | — | |
| SCHEMBL12085735 | 0.74 | NAMPT (0.35) | — | |
| SCHEMBL493857 | 0.74 | CA1 (0.53) | — | |
| SCHEMBL715968 | 0.74 | — | — | |
| SCHEMBL7741531 | 0.72 | — | — | |
| SCHEMBL439255 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130330779-A1 | FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS AND VALEROLACTONE AND DERIVATIVES THEREOF | ARZEDA CORPORATION | 2013-12-12 | — | — | US | claimed |
| EP-2611764-A1 | FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF | Arzeda Corp. (US) | 2013-07-10 | — | — | EP | claimed |
| CN-103180279-A | Fermentation pathways for the production of levulinic acid, levulinic acid esters, valerolactone, and derivatives thereof | ARZEDA CORP | 2013-06-26 | — | — | CN | claimed |
| WO-2012030860-A1 | FERMENTATION ROUTE FOR THE PRODUCTION OF LEVULINIC ACID, LEVULINATE ESTERS, VALEROLACTONE, AND DERIVATIVES THEREOF | ARZEDA CORP. (US) | 2012-03-08 | — | — | WO | claimed |
| US-20060025600-A1 | Process for preparing zolmitriptan compounds | INKE, S.A. (ES) | 2006-02-02 | — | — | US | claimed |
| EP-0859002-B1 | Process for producing chloroacetylaminothiazoleacetic acid derivatives | TOKUYAMA CORP (JP) | 2003-07-02 | — | — | EP | claimed |
| US-5389602-A | PLANT GROWTH REGULATORS | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-14 | — | — | US | claimed |
| EP-0345635-B1 | Herbicidal tetrahydropyran-2,4-diones | BASF AG (DE) | 1994-10-05 | — | — | EP | claimed |
| EP-0345635-A1 | Herbicidal tetrahydropyran-2,4-diones | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | claimed |
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| US-20240092745-A1 | DRUGS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS | Graybug Vision, Inc. (US) | 2024-03-21 | — | — | US | disclosed |
| US-11548861-B2 | Drugs and compositions for the treatment of ocular disorders | Graybug Vision, Inc. (US) | 2023-01-10 | — | — | US | disclosed |
| EP-3898645-A1 | 2-FLUORINATED BILE ACIDS FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NZP UK Limited (GB) | 2021-10-27 | — | — | EP | disclosed |
| EP-3723750-A1 | DRUGS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2020-10-21 | — | — | EP | disclosed |
| US-4859234-A | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and phenoxyalkanoic acids, salts, amides and esters therof as antidotes | ICI AMERICAS INC. (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0164698-B1 | PROCESS FOR EPIMERIZATION AT C6 OF 3,4,5,6-TETRA-HYDRO-2H-PYRAN-2-ONE | MERCK & CO. INC. (US) | 1989-07-19 | — | — | EP | disclosed |
| EP-0298680-A2 | Herbicidal compositions of acylated 1,3-dicarbonyl herbicides and antidotes therefor | ZENECA INC. (US) | 1989-01-11 | — | — | EP | disclosed |
| CN-87104096-A | The 4-benzoyl-3 that replaces, 5-dioxo tetrahydropyrans and 4-benzoyl-3,5-dioxo tetrahydric thiapyran | — | 1988-04-20 | — | — | CN | disclosed |
| US-4695673-A | Process for the production of acylated 1,3-dicarbonyl compounds | STAUFFER CHEMICAL COMPANY (US) | 1987-09-22 | — | — | US | disclosed |
| EP-0164698-A2 | Process for epimerization at C6 of 3,4,5,6-tetra-hydro-2H-pyran-2-one | MERCK & CO. INC. (US) | 1985-12-18 | — | — | EP | disclosed |