Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.54 |
| ▸ | HTR2C | P28335 | 15/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064199 | 0.89 | HTR2A (0.55) | HTR2AHTR2C | |
| SCHEMBL16531690 | 0.86 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL16531662 | 0.86 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL16531325 | 0.86 | HTR2A (0.55) | HTR2AHTR2C | |
| SCHEMBL16531742 | 0.85 | HTR2A (0.54) | HTR2AHTR2C | |
| SCHEMBL16530874 | 0.84 | HTR2A (0.52) | HTR2AHTR2C | |
| SCHEMBL16531733 | 0.81 | HTR2A (0.54) | HTR2AHTR2C | |
| SCHEMBL16531720 | 0.80 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL16531643 | 0.80 | HTR2A (0.51) | HTR2AHTR2C | |
| SCHEMBL16531412 | 0.79 | HTR2A (0.57) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018371-B1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2015-03-04 | — | — | EP | claimed |