Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.57 |
| ▸ | HTR2C | P28335 | 15/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16531662 | 0.94 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL885445 | 0.89 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL16530874 | 0.88 | HTR2A (0.52) | HTR2AHTR2C | |
| SCHEMBL16531558 | 0.86 | HTR2A (0.54) | HTR2AHTR2C | |
| SCHEMBL16531742 | 0.86 | HTR2A (0.54) | HTR2AHTR2C | |
| SCHEMBL885683 | 0.85 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL16531720 | 0.82 | HTR2A (0.58) | HTR2AHTR2C | |
| SCHEMBL16531412 | 0.80 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL20778743 | 0.80 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL16531733 | 0.80 | HTR2A (0.54) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018371-B1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2015-03-04 | — | — | EP | claimed |
| US-8945510-B2 | Radiolabeled glutaminyl cyclase (QC) inhibitors and uses of same | PROBIODRUG AG (DE) | 2015-02-03 | — | — | US | disclosed |