Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.53 |
| ▸ | HTR2C | P28335 | 16/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16531756 | 0.86 | HTR2A (0.51) | HTR2AHTR2C | |
| SCHEMBL16531717 | 0.80 | HTR2A (0.61) | HTR2AHTR2CKCNH2 | |
| SCHEMBL16531744 | 0.80 | HTR2A (0.57) | HTR2AHTR2CKCNH2 | |
| SCHEMBL884276 | 0.76 | HTR2A (0.65) | HTR2AHTR2C | |
| Cyclopentane SCHEMBL16531358 | 0.76 | HTR2A (0.69) | HTR2AHTR2C | |
| SCHEMBL2064282 | 0.75 | HTR2A (0.52) | HTR2AHTR2C | |
| SCHEMBL16531103 | 0.74 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL16531047 | 0.74 | HTR2A (0.55) | HTR2AHTR2C | |
| SCHEMBL2064559 | 0.74 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL16531783 | 0.73 | HTR2A (0.57) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018371-B1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2015-03-04 | — | — | EP | claimed |