Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16532154 | 0.92 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL16531996 | 0.90 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL17907310 | 0.86 | DGAT1 (0.60) | DGAT1 | |
| SCHEMBL16532157 | 0.86 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL16532138 | 0.79 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL17907344 | 0.78 | DGAT1 (0.56) | DGAT1 | |
| SCHEMBL16532155 | 0.77 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL16532086 | 0.77 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL17907321 | 0.76 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL16532156 | 0.76 | DGAT1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015024486-A1 | DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF | 南京明德新药研发股份有限公司 (CN) | 2015-02-26 | — | — | WO | disclosed |