Fluorescein

Fluorescein

SCHEMBL16533

O=C1OC2(c3ccc(O)cc3Oc3cc(O)ccc32)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 8/20 1.00
MAPT P10636 4/20 1.00
MEN1 O00255 4/20 1.00
KMT2A Q03164 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
HTT P42858 2/20 1.00
HPGD P15428 2/20 1.00
RECQL P46063 2/20 1.00
BLM P54132 2/20 1.00
PRMT1 Q99873 2/20 1.00
ACE2 Q9BYF1 2/20 1.00
CYP2C19 P33261 1/20 1.00
SMAD3 P84022 1/20 1.00
LMNA P02545 3/20 0.69
GPR55 Q9Y2T6 2/20 0.69
ALOX12 P18054 2/20 0.69
POLB P06746 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
ALDH1A1 P00352 3/20 0.62
USP2 O75604 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorescein SCHEMBL30272223 1.00 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3645090 1.00 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29388667 1.00 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL29371199 1.00 FTO (1.00) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL538249 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL21358817 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL1425151 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL21410711 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL20503455 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1
Fluorescein SCHEMBL3293893 0.98 FTO (0.97) FTOMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 354792 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119269789-A Dopaminergic neuron precursor cell marker and application thereof 深圳华大生命科学研究院 2025-01-07 CN claimed
CN-117737161-B Adiponectin antibody magnetic microsphere and adiponectin assay kit 广东优尼德生物科技有限公司 2025-01-03 CN claimed
US-12178885-B2 Method for mediating targeted delivery of a composition to the brain of a subject in need thereof FUDAN UNIVERSITY (CN) 2024-12-31 US claimed
CN-119198504-A Method for detecting systemic lupus erythematosus immunity map based on full spectrum flow cytometry 上海交通大学医学院附属仁济医院 2024-12-27 CN claimed
WO-2024263607-A2 ULTRA-BRIGHT NANOPARTICLE FLUORESCENT DYE COMPLEXES CYTEK BIOSCIENCES, INC. (US) 2024-12-26 WO claimed
US-20240424149-A1 Ophthalmic Compositions, and Ocular Uses Thereof, of Indigo Carmine ZEBRA BIOTECH PTY LTD (AU) 2024-12-26 US claimed
CN-114354941-B Method for establishing cyclic transmission of phytoplasma between mediator and plant through immune labeling 黑龙江省农业科学院水稻研究所 2024-12-20 CN claimed
US-20240415991-A1 System, Method, and Device for Facilitating Effective Decontamination as Part of a Decontamination Event Rememdia LC 2024-12-19 US claimed
US-12168797-B2 Signal encoding and decoding in multiplexed biochemical assays CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2024-12-17 US claimed
US-20240410906-A1 DHEAS ASSAY, REAGENTS FOR SAME, AND METHODS OF PRODUCTION AND USE THEREOF SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2024-12-12 US claimed
US-4075015-A Light sensitive mass and process for its production SWISS ALUMINIUM LTD. (CH) 1978-02-21 US claimed
US-4029756-A RADIOIMMUNOASSAY RESEARCH CORPORATION (US) 1977-06-14 US claimed
US-4001027-A FLUORESCEIN TYPE PIGMENT BORDEN, INC. (US) 1977-01-04 US claimed
US-3998943-A Double receptor fluorescent immunoassay SYVA COMPANY (US) 1976-12-21 US claimed
US-3977953-A PHOTOSENSITIZED OXIDATION OF LUPULONES ATLANTIC RESEARCH INSTITUTE LTD. (BA) 1976-08-31 US claimed
US-3972231-A Method for measuring velocity and direction of currents in a body of water THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-08-03 US claimed
US-3954584-A Photopolymerizable vinylurethane liquid composition KANSAI PAINT COMPANY (JA) 1976-05-04 US claimed
US-3939350-A Fluorescent immunoassay employing total reflection for activation BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1976-02-17 US claimed
US-3936190-A Fluorescence spectrophotometer for absorption spectrum analysis THE PERKIN-ELMER CORPORATION (US) 1976-02-03 US claimed
US-3935834-A Frost line indicator THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1976-02-03 US claimed