SCHEMBL165334

SCHEMBL165334

c1ccc(-c2cccc3[nH]nnc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.49
LIMK1 P53667 2/20 0.41
CLK4 Q9HAZ1 2/20 0.41
PLK4 O00444 1/20 0.41
MAPK9 P45984 1/20 0.41
AKT3 Q9Y243 1/20 0.41
MAP4K4 O95819 1/20 0.40
CSF1R P07333 1/20 0.40
FGFR1 P11362 1/20 0.40
PDGFRA P16234 1/20 0.40
LTK P29376 1/20 0.40
KDR P35968 1/20 0.40
MAPK8 P45983 1/20 0.40
CSNK1A1 P48729 1/20 0.40
CDK5 Q00535 1/20 0.40
ACVR1 Q04771 1/20 0.40
TNK2 Q07912 1/20 0.40
AURKB Q96GD4 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
CNR2 P34972 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669794 1.00 METAP2 (0.49) METAP2LIMK1CLK4PLK4MAPK9
SCHEMBL27688933 0.98 METAP2 (0.47) METAP2LIMK1CLK4PLK4MAPK9
SCHEMBL27708730 0.98 METAP2 (0.47) METAP2LIMK1CLK4PLK4MAPK9
Chloromethane SCHEMBL27297588 0.95 METAP2 (0.45) METAP2LIMK1CLK4PLK4MAPK9
SCHEMBL17927231 0.93 METAP2 (0.50) METAP2LIMK1CLK4PLK4MAPK9
Allyl Alcohol SCHEMBL11137392 0.87 METAP2 (0.40) METAP2LIMK1CLK4PLK4MAPK9
SCHEMBL31619990 0.86 METAP2 (0.38) METAP2CLK4PLK4MAPK9AKT3
SCHEMBL30556736 0.86 METAP2 (0.38) METAP2CLK4PLK4MAPK9AKT3
SCHEMBL3977747 0.84 MGAM (0.40) METAP2KDRALDH1A1HPGDKDM4E
SCHEMBL2249700 0.84 KDR (0.39) METAP2CLK4PLK4MAPK9AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3908 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630744-B2 Polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2026-05-19 US claimed
EP-4727513-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, A SEMI-CRYSTALLINE POLYMER CONTAINING AT LEAST ONE ALKYL ACRYLATE CHAIN AND A SCLEROGLUCAN GUM L'OREAL (FR) 2026-04-22 EP claimed
EP-4518849-B1 COMPOSITION FOR TOPICAL APPLICATION FOR THE PHOTOTHERAPEUTIC TREATMENT OF INFLAMMATORY-BASED SKIN DISEASES GIULIANI SPA (IT) 2026-04-08 EP claimed
US-12590224-B2 Chemical mechanical polishing compositions and methods of use thereof FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2026-03-31 US claimed
US-20260042976-A1 COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM ELECTRONIC MAT USA INC (US) 2026-02-12 US claimed
EP-4688987-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2026-02-11 EP claimed
EP-4653506-A1 CHEMICAL MECHANICAL POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A, Inc. (US) 2025-11-26 EP claimed
EP-4647474-A2 CHEMICAL MECHANICAL POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM Electronic Materials U.S.A., Inc. (US) 2025-11-12 EP claimed
US-20250333622-A1 POLISHING COMPOSITIONS AND METHODS OF USE THEREOF FUJIFILM ELECTRONIC MAT USA INC (US) 2025-10-30 US claimed
US-20250329566-A1 ADHESIVE COMPOSITION FOR RELEASE BY LIGHT IRRADIATION, LAMINATE, AND METHOD FOR PRODUCING PROCESSED SEMICONDUCTOR SUBSTRATE OR ELECTRONIC DEVICE LAYER NISSAN CHEMICAL CORPORATION (JP) 2025-10-23 US claimed
US-4631066-A HEAT TREATMENT WITH UREA, THIOUREA MIXTURE TEIJIN LIMITED (JP) 1986-12-23 US claimed
US-4614753-A Light-resistant and weather-proof polyolefin foams DYNAMIT NOBEL AG (DE) 1986-09-30 US claimed
WO-1986004342-A1 OXYGEN-PERMEABLE LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
WO-1986004343-A1 EXTENDED-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
WO-1986004341-A1 CONTINUOUS-WEAR LENSES BAUSCH AND LOMB INCORPORATED (US) 1986-07-31 WO claimed
US-4590221-A WITH PHENOLIC ANTIOXIDANT, BENZOPHENONES AND/OR BENZOTR<IAZOLES, AND STERICALLY HINDERED AMINES DYNAMIT NOBEL AG (DE) 1986-05-20 US claimed
EP-0132402-A2 Method for improving light-resistance of aromatic polyamide fibers TEIJIN LIMITED (JP) 1985-01-30 EP claimed
EP-0006049-B1 TRANSPARENT FILM AND ITS USE FOR WRAPPING GOODS WHICH COULD BE DAMAGED BY ULTRAVIOLET RAYS Société Chimique des Charbonnages (FR) 1983-04-06 EP claimed
US-4289830-A OXYGEN-IMPERVIOUS PACKAGING MATERIAL AMERICAN CAN COMPANY (US) 1981-09-15 US claimed
EP-0006049-A1 Transparent film and its use for wrapping goods which could be damaged by ultraviolet rays Société Chimique des Charbonnages (FR) 1979-12-12 EP claimed