SCHEMBL16537372

SCHEMBL16537372

C=C(C)C(=O)OCCCCC[Si](CCC)(OCC)OCC

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
THRB P10828 1/20 0.46
POLB P06746 1/20 0.42
APEX1 P27695 1/20 0.42
HTT P42858 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ACHE P22303 9/20 0.35
NAAA Q02083 1/20 0.34
ALDH1A1 P00352 1/20 0.33
RAD52 P43351 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FAAH O00519 1/20 0.33
EPHX1 P07099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537891 0.98 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1269949 0.94 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27616681 0.93 TSHR (0.63) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16286556 0.90 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537639 0.90 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7597930 0.89 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537584 0.88 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL19125098 0.88 TSHR (0.60) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537360 0.88 THRB (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL16537844 0.87 TSHR (0.63) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed