SCHEMBL16538069

SCHEMBL16538069

C=C(C)C(=O)OC(C)[Si](CC)(CC)OC

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.40
ALDH1A1 P00352 1/20 0.39
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537042 0.90 TSHR (0.36) TSHRALDH1A1THRB
SCHEMBL16537091 0.86 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL16537265 0.84 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL16537763 0.82 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL16537274 0.81 TSHR (0.39) TSHRALDH1A1THRB
SCHEMBL16536523 0.81 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL16537195 0.79 TSHR (0.35) TSHRTHRB
SCHEMBL16537167 0.78 ALDH1A1 (0.39) TSHRALDH1A1THRB
SCHEMBL193159 0.77 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL16536217 0.76 TSHR (0.38) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed