Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16429588 | 0.92 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHRLMNATRPM8 | |
| SCHEMBL1230695 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL9798865 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL2470289 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL9798861 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL1230210 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL6669258 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL1229471 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL1230725 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB | |
| SCHEMBL1228691 | 0.82 | TSHR (0.35) | ALDH1A1TSHRLMNAOPRM1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101035818-B | Ziegler-natta catalyst, method for the production thereof and use thereof for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-08-17 | — | — | CN | claimed |
| US-7329626-B2 | Ziegler-Natta catalyst, preparation, and use for the polymerization of alkenes | LUMMUS NOVOLEN TECHNOLOGY GMBH (NL) | 2008-02-12 | — | — | US | claimed |
| CN-101035818-A | Ziegler-natta catalyst, method for the production thereof and use thereof for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-09-12 | — | — | CN | claimed |
| EP-1805230-A1 | ZIEGLER-NATTA CATALYST, PREPARATION, AND USE FOR THE POLYMERIZATION OF ALKENES | Novolen Technology Holdings, C.V. (NL) | 2007-07-11 | — | — | EP | claimed |
| US-7232785-B2 | Solid catalytic component and catalytic system of the ziegler-natta type, process for their preparation and their use in the polymerization of alk-1-enes | ABB LUMMUS GLOBAL, INC. (US) | 2007-06-19 | — | — | US | claimed |
| WO-2006028736-A1 | ZIEGLER-NATTA CATALYST, PREPARATION, AND USE FOR THE POLYMERIZATION OF ALKENES | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2006-03-16 | — | — | WO | claimed |
| US-20060052237-A1 | Ziegler-Natta catalyst, preparation, and use for the polymerization of alkenes | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2006-03-09 | — | — | US | claimed |
| US-20250376547-A1 | CONTINUOUS OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF AN ANTISTATIC AGENT | BASELL POLYOLEFINE GMBH (DE) | 2025-12-11 | — | — | US | disclosed |
| EP-4551615-B1 | CONTINUOUS OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF AN ANTISTATIC AGENT | BASELL POLYOLEFINE GMBH (DE) | 2025-12-03 | — | — | EP | disclosed |
| EP-3902849-B1 | PROCESS FOR PREPARATION OF POLYETHYLENE | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2025-10-01 | — | — | EP | disclosed |
| EP-4551615-A1 | CONTINUOUS OLEFIN POLYMERIZATION PROCESS IN THE PRESENCE OF AN ANTISTATIC AGENT | Basell Polyolefine GmbH (DE) | 2025-05-14 | — | — | EP | disclosed |
| US-12240963-B2 | Process for preparation of polyethylene | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2025-03-04 | — | — | US | disclosed |
| US-12103988-B2 | Gas-phase process for preparing ethylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2024-10-01 | — | — | US | disclosed |
| US-6524995-B2 | Used for preparing polypropylene homo/copolymers; films, fibers, moldings; efficiency | BASELL POLYPROPYLENE GMBH (DE) | 2003-02-25 | — | — | US | disclosed |
| US-6495634-B2 | SOLUBILITY VARIATIONS USED TO SEPARATE PROPYLENE POLYMERS CONTAINING A MATRIX OF HOMOPOLYMER AND A COPOLYMER WITH ALKENES ACCORDING TO ISOTACTICITY AND DISTRIBUTION BY DISSOLVING IN BOILING XYLENE, COOLING AND HEATING; RIGIDITY | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-17 | — | — | US | disclosed |
| US-20020173602-A1 | Random propylene copolymers | APPLEYARD DAVID (GB) | 2002-11-21 | — | — | US | disclosed |
| US-20010020073-A1 | Novel catalyst systems of the Ziegler-Natta type | BASELL POLYPROPYLEN GMBH (DE) | 2001-09-06 | — | — | US | disclosed |
| US-20010012874-A1 | PROPYLENE POLYMERS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2001-08-09 | — | — | US | disclosed |
| US-6221984-B1 | Random propylene copolymer | BASF AKTIENGESELLSCHAFT (DE) | 2001-04-24 | — | — | US | disclosed |
| US-6191223-B1 | Polymer blends | TAGOR GMBH (DE) | 2001-02-20 | — | — | US | disclosed |