Lawsone

Lawsone

SCHEMBL16541

O=C1C=C(O)C(=O)c2ccccc21

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.68
MAPK1 P28482 5/20 0.68
KDM4E B2RXH2 4/20 0.68
ALDH1A1 P00352 3/20 0.68
CYP3A4 P08684 2/20 0.68
HPGD P15428 2/20 0.68
PTPN22 Q9Y2R2 1/20 0.68
KMT2A Q03164 6/20 0.56
MEN1 O00255 5/20 0.56
CDC25B P30305 3/20 0.56
BLM P54132 3/20 0.56
MAOA P21397 3/20 0.56
LMNA P02545 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
IDO1 P14902 2/20 0.56
CDC25A P30304 2/20 0.56
USP2 O75604 2/20 0.56
ATM Q13315 2/20 0.56
PLIN1 O60240 2/20 0.56
PLIN5 Q00G26 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lawsone SCHEMBL6849999 1.00 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL5826345 1.00 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL29350263 1.00 MAPT (0.68) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052663 0.98 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052709 0.98 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL6052722 0.98 MAPT (0.65) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL9136705 0.96 MAPT (0.63) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL918203 0.94 MAPT (0.61) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL19742249 0.92 MAPT (0.59) MAPTMAPK1KDM4EALDH1A1CYP3A4
Lawsone SCHEMBL2720419 0.92 MAPT (0.59) MAPTMAPK1KDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13228 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075370-A Composite hair dye and preparation method and application thereof 2026-05-26 CN claimed
CN-122075369-A Mild hair dye and preparation method and application thereof 2026-05-26 CN claimed
EP-4356934-B1 METHOD FOR ADJUSTING ACTIVITY OF BIOFILM NAT INST MATERIALS SCIENCE (JP) 2026-05-20 EP claimed
US-20260130837-A1 SPF BOOSTER AND SUNCARE FORMULATIONS INCLUDING SAME DOW SILICONES CORP (US) 2026-05-14 US claimed
EP-3600224-B1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2026-05-06 EP claimed
WO-2026089857-A1 METHOD OF PREPARING AND USING A SKIN CARE COMPOSITION DOW SILICONES CORPORATION (US) 2026-04-30 WO claimed
WO-2026089856-A1 METHOD OF PREPARING AND USING A SKIN CARE FORMULATION DOW SILICONES CORPORATION (US) 2026-04-30 WO claimed
EP-4728089-A1 METHOD AND DEVICE FOR DETECTION OF AN ANALYTE IN A SAMPLE Davis, Paul (GB) 2026-04-22 EP claimed
EP-4482453-B1 COLORANT COMPOSITION COMPRISING LEUCOINDIGO FOR COLORING FIBERS AND FABRICS LABORATOIRE BIOSTHETIQUE KOSMETIK GMBH & CO KG (DE) 2026-04-08 EP claimed
US-20260076889-A1 POLYESTER FILM-FORMING POLYMERS FOR ALCOHOLBASED SUNSCREEN FORMULATIONS NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2026-03-19 US claimed
US-4432769-A MADE BY REACTING 3-AMINO-4-NITRO-CHLOROBENZENE WITH GLYCEROL L'OREAL (FR) 1984-02-21 US claimed
US-4343871-A GROUP IA METAL ANODE AND CATHODE FORMED OF ORGANIC COMPOUND HAVINGPI-ELECTRON CONJUGATED SYSTEM NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1982-08-10 US claimed
US-4340662-A PHOTOSENSITIVE FILMS ENERGY CONVERSION DEVICES, INC. (US) 1982-07-20 US claimed
US-4324553-A OXIDATION COLOR DYES L'OREAL (FR) 1982-04-13 US claimed
US-4281058-A A PHOTOSENSITIVE COMPLEX OF THE TELLURIUM COMPOUND AND A GLYCEROL ETHER OR THIOETHER; NONSILVER PHOTOGRAPHY ENERGY CONVERSION DEVICES, INC. (US) 1981-07-28 US claimed
US-4268264-A ORTHO PRECURSORS SELECTED FROM AROMATIC DIAMINES, AMINOPHENOL, DIPHENOL, AND PHENYLENEDIAMINE L'OREAL (FR) 1981-05-19 US claimed
US-4190064-A SIMULTANEOUS TONING, SHAMPOO, AND CONDITIONING DEL LABORATORIES, INC. (US) 1980-02-26 US claimed
EP-0002228-A2 Hydroxy naphthoquinone derivatives, their preparations for treating and preventing theileriosis in cattle and sheep, processes for their synthesis; naphthoquinone derivatives THE WELLCOME FOUNDATION LIMITED (GB) 1979-06-13 EP claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
US-3975285-A LONG LIFE DYNAMIC LIGHT SCATTERING PROPERTIES HODOGAYA CHEMICAL CO., LTD. (JA) 1976-08-17 US claimed