Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | CDC25A | P30304 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lawsone SCHEMBL5826345 | 0.96 | MAPT (0.68) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL6849999 | 0.96 | MAPT (0.68) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL16541 | 0.96 | MAPT (0.68) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL29350263 | 0.96 | MAPT (0.68) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL27565471 | 0.93 | MAPT (0.65) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL6052663 | 0.93 | MAPT (0.65) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL6052709 | 0.93 | MAPT (0.65) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL6052722 | 0.93 | MAPT (0.65) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL918203 | 0.89 | MAPT (0.61) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 | |
| Lawsone SCHEMBL19742249 | 0.88 | MAPT (0.59) | MAPTMAPK1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393857-A | Condensation product of hydrazine and a quinone as antideposit and antiscaling coating on inside walls of vessels used in addition polymerization | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-02-28 | — | — | US | disclosed |