SCHEMBL1654101

SCHEMBL1654101

CC(C)(C)C[Mg]Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1765810 0.69
SCHEMBL20899788 0.67
SCHEMBL1765361 0.65
SCHEMBL6563825 0.64
SCHEMBL1655095 0.61
SCHEMBL5238 0.61
SCHEMBL1765686 0.60
SCHEMBL6564465 0.59
SCHEMBL6054 0.56
SCHEMBL626928 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
JP-8143491-A None JP disclosed
CN-116917280-B Tetrahydronaphthalene compound, preparation method thereof and application thereof in medicine 江苏恒瑞医药股份有限公司 2026-05-12 CN disclosed
EP-4727647-A1 GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF The Broad Institute Inc. (US) 2026-04-22 EP disclosed
US-20260103465-A1 GLYCOGEN SYNTHASE KINASE 3 INHIBITORS AND USES THEREOF THE BROAD INSTITUTE, INC. (US) 2026-04-16 US disclosed
US-12544747-B2 Processes for producing fluorided solid oxides and uses thereof in metallocene-based catalyst systems CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-02-10 US disclosed
US-12516137-B2 High porosity fluorided silica-coated alumina activator-supports and uses thereof in metallocene-based catalyst systems for olefin polymerization CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2026-01-06 US disclosed
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO disclosed
US-20250257155-A1 HIGH POROSITY FLUORIDED SILICA-COATED ALUMINA ACTIVATOR-SUPPORTS AND USES THEREOF IN METALLOCENE-BASED CATALYST SYSTEMS FOR OLEFIN POLYMERIZATION CHEVRON PHILLIPS CHEMICAL COMPANY LP 2025-08-14 US disclosed
US-20250177966-A1 Processes for Producing Fluorided Solid Oxides and Uses Thereof in Metallocene-Based Catalyst Systems CHEVRON PHILLIPS CHEMICAL COMPANY LP 2025-06-05 US disclosed
EP-0651643-A1 17-ALKYLKETONE STEROIDS USEFUL AS 5-$g(a)-REDUCTASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1995-05-10 EP disclosed
CN-1095382-A The new A of cyanines family ring steroide SMITHKLINE BEECHAM CORP (US) 1994-11-23 CN disclosed
WO-1994000125-A1 17-ALKYLKETONE STEROIDS USEFUL AS 5-α-REDUCTASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1994-01-06 WO disclosed
CN-1071917-A Quinazoline derivant as human immunodeficiency virus reversed transcriptive enzyme antagonist MERCK & CO INC (US) 1993-05-12 CN disclosed
EP-0530994-A1 Quinazoline derivatives as inhibitors of HIV reverse transcriptase MERCK & CO. INC. (US) 1993-03-10 EP disclosed
WO-1993004047-A1 QUINAZOLINE DERIVATIVES AS INHIBITORS OF HIV REVERSE TRANSCRIPTASE MERCK & CO., INC. (US) 1993-03-04 WO disclosed
EP-0245053-B1 HETEROCYCLIC FUSED TRICYCLIC COMPOUNDS ICI AMERICAS INC. (US) 1992-11-25 EP disclosed
US-5118688-A TETRAHYDROPYRIDOQUINOLONE DERIVATIVES USEFUL AS ANXIOLYTIC AGENTS ICI AMERICAS INC. (US) 1992-06-02 US disclosed
US-4975435-A Certain 1H-pyrrold[3,4-b]quinolin-1-one-9-amino-2,3-dihydro derivatives useful for treating anxiety ICI AMERICAS INC. (US) 1990-12-04 US disclosed
EP-0245053-A1 Heterocyclic fused tricyclic compounds ICI AMERICAS INC. (US) 1987-11-11 EP disclosed