Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 3/20 | 0.53 |
| ▸ | CD14 | P08571 | 3/20 | 0.53 |
| ▸ | LY96 | Q9Y6Y9 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | CD69 | Q07108 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | PTPRB | P23467 | 4/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.42 |
| ▸ | GSTA1 | P08263 | 6/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 6/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545619 | 0.93 | TLR4 (0.56) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL16545624 | 0.84 | CD69 (0.75) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL16545620 | 0.84 | CD69 (0.59) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL14617492 | 0.84 | TLR4 (0.57) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL14617494 | 0.82 | PTPRC (0.57) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL30388098 | 0.79 | ELANE (0.51) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL2471228 | 0.74 | GABRA1 (0.50) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL29517201 | 0.74 | GABRA1 (0.50) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL13620669 | 0.74 | GABRA1 (0.50) | TLR4CD14LY96ELANECD69 | |
| SCHEMBL30547266 | 0.74 | GABRA1 (0.50) | TLR4CD14LY96ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITÉ PARIS CITÉ (FR) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | TLR4 2284/4885CD14 1487/4885LY96 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.