Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 7/20 | 0.38 |
| ▸ | CD14 | P08571 | 7/20 | 0.38 |
| ▸ | LY96 | Q9Y6Y9 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16545619 | 0.80 | TLR4 (0.56) | MAOBTLR4CD14LY96APP | |
| SCHEMBL16545616 | 0.76 | MAOB (0.38) | MAOBTLR4CD14LY96MAPT | |
| SCHEMBL16545609 | 0.74 | TLR4 (0.53) | MAOBTLR4CD14LY96ELANE | |
| SCHEMBL13987039 | 0.74 | TLR4 (0.51) | TLR4CD14LY96ALDH1A1MAPT | |
| SCHEMBL16545620 | 0.70 | CD69 (0.59) | MAOBTLR4CD14LY96ELANE | |
| SCHEMBL16545624 | 0.70 | CD69 (0.75) | MAOBTLR4CD14LY96ELANE | |
| SCHEMBL16545621 | 0.69 | CD69 (0.47) | MAOBTLR4CD14LY96MAPT | |
| SCHEMBL26278020 | 0.67 | MAOB (0.51) | MAOBKCNH2APP | |
| SCHEMBL2560925 | 0.67 | MAOB (0.51) | MAOBALDH1A1MAPTAPPKMT2A | |
| SCHEMBL21497155 | 0.64 | APP (0.40) | MAOBALDH1A1MAPTHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITÉ PARIS CITÉ (FR) | 2015-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150064455-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | MAOB 1971/4885TLR4 2284/4885CD14 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.