Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 12/20 | 0.35 |
| ▸ | ITK | Q08881 | 7/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2806154 | 0.86 | REN (0.34) | RENITK | |
| SCHEMBL2809388 | 0.81 | REN (0.46) | REN | |
| SCHEMBL2813578 | 0.80 | REN (0.44) | RENITKSLC22A12 | |
| SCHEMBL13132302 | 0.78 | REN (0.40) | RENITKSLC22A12 | |
| SCHEMBL13132222 | 0.77 | REN (0.44) | REN | |
| SCHEMBL13132994 | 0.77 | REN (0.44) | REN | |
| SCHEMBL16546319 | 0.77 | REN (0.51) | REN | |
| SCHEMBL13132996 | 0.77 | REN (0.44) | REN | |
| SCHEMBL2810132 | 0.75 | REN (0.41) | RENITKSLC22A12 | |
| SCHEMBL13131761 | 0.74 | REN (0.64) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |