Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16546319 | 0.81 | REN (0.51) | RENMEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL27795778 | 0.81 | REN (0.38) | RENL3MBTL1P2RY12FDFT1 | |
| SCHEMBL2830341 | 0.79 | REN (0.53) | REN | |
| SCHEMBL2809114 | 0.79 | REN (0.34) | RENL3MBTL1 | |
| SCHEMBL2807067 | 0.78 | REN (0.37) | REN | |
| SCHEMBL13132117 | 0.76 | REN (0.49) | REN | |
| SCHEMBL2809721 | 0.76 | BCHE (0.36) | REN | |
| SCHEMBL2813602 | 0.72 | REN (0.41) | REN | |
| SCHEMBL2805717 | 0.72 | REN (0.47) | REN | |
| SCHEMBL2863011 | 0.71 | REN (0.37) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |