Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13132572 | 1.00 | REN (0.52) | RENKCNH2 | |
| SCHEMBL2808501 | 0.96 | REN (0.50) | RENKCNH2 | |
| SCHEMBL13132723 | 0.92 | REN (0.57) | REN | |
| SCHEMBL13132771 | 0.92 | REN (0.53) | REN | |
| SCHEMBL13132216 | 0.92 | REN (0.52) | REN | |
| SCHEMBL13132492 | 0.92 | REN (0.52) | RENKCNH2 | |
| SCHEMBL16546326 | 0.92 | REN (0.52) | REN | |
| SCHEMBL13132562 | 0.92 | REN (0.52) | RENKCNH2 | |
| SCHEMBL13132774 | 0.91 | REN (0.52) | REN | |
| SCHEMBL13132214 | 0.91 | REN (0.52) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975252-B2 | Morpholine derivative | SHANGHAI PHARMACEUTICALS HOLDING CO., LTD. (CN) | 2015-03-10 | — | — | US | disclosed |