Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 2/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654481 | 0.82 | NPSR1 (0.41) | PDK1DYRK1AADORA2AADORA1AXL | |
| SCHEMBL14774637 | 0.79 | ADORA2A (0.41) | DYRK1AADORA2AADORA1JAK3KMO | |
| SCHEMBL3655720 | 0.75 | ADORA2A (0.41) | ADORA2AADORA1 | |
| SCHEMBL31514673 | 0.74 | PRKCI (0.41) | PDK1DYRK1AADORA2AADORA1AXL | |
| SCHEMBL691603 | 0.74 | PRKCI (0.44) | PDK1DYRK1AADORA2AADORA1AXL | |
| SCHEMBL29700716 | 0.74 | PRKCI (0.44) | PDK1DYRK1AADORA2AADORA1AXL | |
| SCHEMBL27912585 | 0.73 | AXL (0.33) | PDK1DYRK1AADORA2AADORA1AXL | |
| SCHEMBL29495204 | 0.72 | CD38 (0.39) | DYRK1AKMOAURKATPX2 | |
| SCHEMBL9918650 | 0.72 | AXL (0.41) | AXLPRKCIJAK3KMONOTUM | |
| SCHEMBL3491733 | 0.71 | JAK3 (0.59) | JAK3NOTUMJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488518-A2 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
| CN-102574849-A | Herbicidal compounds | SYNGENTA LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | PDK1 2754/4885DYRK1A 520/4885ADORA2A 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.