Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 13/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16553689 | 0.91 | NR1H2 (0.66) | NR1H2PTGS2NR1H3 | |
| SCHEMBL25878810 | 0.86 | NR1H2 (0.68) | NR1H2PTGS2NR1H3 | |
| SCHEMBL29496560 | 0.86 | NR1H2 (0.70) | NR1H2PTGS2NR1H3 | |
| SCHEMBL16566124 | 0.86 | NR1H2 (0.70) | NR1H2PTGS2NR1H3 | |
| SCHEMBL17970790 | 0.85 | NR1H2 (0.72) | NR1H2PTGS2NR1H3 | |
| SCHEMBL17970771 | 0.84 | NR1H2 (0.60) | NR1H2PTGS2NR1H3 | |
| SCHEMBL16553554 | 0.82 | NR1H2 (0.77) | NR1H2PTGS2NR1H3 | |
| SCHEMBL15242777 | 0.82 | NR1H2 (0.57) | NR1H2PTGS2 | |
| SCHEMBL29496569 | 0.82 | NR1H2 (0.73) | NR1H2PTGS2NR1H3 | |
| SCHEMBL16566131 | 0.82 | NR1H2 (0.73) | NR1H2PTGS2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212127-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20230212127-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS, INC. | 2023-07-06 | — | — | US | disclosed |
| US-20220388963-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS INC (US) | 2022-12-08 | — | — | US | disclosed |
| US-20220388963-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS INC (US) | 2022-12-08 | — | — | US | disclosed |
| US-20220106274-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS, INC. | 2022-04-07 | — | — | US | disclosed |
| US-11034657-B2 | Liver X receptor (LXR) modulators | ELLORA THERAPEUTICS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| US-11034657-B2 | Liver X receptor (LXR) modulators | ELLORA THERAPEUTICS, INC. (US) | 2021-06-15 | — | — | US | disclosed |
| EP-3041835-B1 | LIVER X RECEPTOR (LXR) MODULATORS | ELLORA THERAPEUTICS INC (US) | 2020-04-08 | — | — | EP | disclosed |
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-3626712-A2 | LIVER X RECEPTOR (LXR) MODULATORS | Ellora Therapeutics, Inc. (US) | 2020-03-25 | — | — | EP | disclosed |
| US-20190169131-A1 | LIVER X RECEPTOR (LXR) MODULATORS | RALEXAR THERAPEUTICS, INC. | 2019-06-06 | — | — | US | disclosed |
| US-20190169131-A1 | LIVER X RECEPTOR (LXR) MODULATORS | RALEXAR THERAPEUTICS, INC. | 2019-06-06 | — | — | US | disclosed |
| US-10246419-B2 | Liver X receptor (LXR) modulators | RALEXAR THERAPEUTICS, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-10246419-B2 | Liver X receptor (LXR) modulators | RALEXAR THERAPEUTICS, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-20180346427-A1 | LIVER X RECEPTOR (LXR) MODULATORS | RALEXAR THERAPEUTICS, INC. | 2018-12-06 | — | — | US | disclosed |
| US-20160221956-A1 | Liver X Receptor (LXR) Modulators | ALEXAR THERAPEUTICS, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| US-20160221956-A1 | Liver X Receptor (LXR) Modulators | ALEXAR THERAPEUTICS, INC. (US) | 2016-08-04 | — | — | US | disclosed |
| EP-3041835-A1 | LIVER X RECEPTOR (LXR) MODULATORS | Alexar Therapeutics, Inc. (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015035015-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ALEXAR THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2015035015-A1 | LIVER X RECEPTOR (LXR) MODULATORS | ALEXAR THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246419-B2 | Liver X receptor (LXR) modulators | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20220106274-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20160221956-A1 | Liver X Receptor (LXR) Modulators | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20190169131-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20180346427-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-11034657-B2 | Liver X receptor (LXR) modulators | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20220388963-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1399/4885NR1H3 2/4885 |
| US-20230212127-A1 | LIVER X RECEPTOR (LXR) MODULATORS | NR1H2, NR1H3, NR1H4 | NR1H2 1/4885PTGS2 1274/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.