Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.64 |
| ▸ | GRM5 | P41594 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16562137 | 0.80 | MAOB (0.69) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905851 | 0.79 | MAOB (0.70) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL2326572 | 0.78 | MAOB (1.00) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL29889798 | 0.78 | MAOB (1.00) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23906027 | 0.73 | MAOB (0.61) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL22451525 | 0.72 | MAOB (0.85) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905149 | 0.72 | MAOB (0.77) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23906233 | 0.72 | MAOB (0.71) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL28030959 | 0.71 | MAOB (0.64) | MAOBGRM5NPC1ALDH1A1HPGD | |
| SCHEMBL23905855 | 0.71 | MAOB (0.65) | MAOBGRM5NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041470-A1 | METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY | Board Of Regents Of the University Of Texas System (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2015035051-A1 | METHODS AND COMPOSITIONS FOR SELECTIVE AND TARGETED CANCER THERAPY | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-03-12 | — | — | WO | disclosed |