SCHEMBL1655460

SCHEMBL1655460

CO/C=C(/C(=O)OC)c1ccccc1COc1cc(C)ccc1C

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALDH1A1 P00352 2/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29404403 1.00 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL42033 1.00 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL29564029 1.00 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL179965 1.00 SMN1; SMN2 (0.45) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL1256265 0.91 MEN1 (0.49) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL29488442 0.90 PTGDR2 (0.46) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL18191247 0.90 PTGDR2 (0.46) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL14637025 0.90 PTGDR2 (0.46) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL14637026 0.90 PTGDR2 (0.46) SMN1; SMN2MEN1KMT2AALDH1A1PTGDR2
SCHEMBL8158229 0.89 MRGPRX4 (0.50) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110105579-A1 Plant Health Composition BASF SE (DE) 2011-05-05 US claimed
JP-2011511033-A 2011-04-07 JP claimed
US-20100272853-A1 Method of Increasing the Milk and/or Meat Quantity of Silage-Fed Animals BASF SE (DE) 2010-10-28 US claimed
EP-2240027-A2 PLANT HEALTH COMPOSITION BASF SE (DE) 2010-10-20 EP claimed
EP-2234481-A2 METHOD OF INCREASING THE MILK AND/OR MEET QUANTITY OF SILAGE-FED ANIMALS BASF SE (DE) 2010-10-06 EP claimed
WO-2009098223-A2 PLANT HEALTH COMPOSITION BASF SE (DE) 2009-08-13 WO claimed
WO-2009080609-A2 METHOD OF INCREASING THE MILK AND/OR MEET QUANTITY OF SILAGE-FED ANIMALS BASF SE (DE) 2009-07-02 WO claimed
EP-4410099-A2 PLANT HEALTH COMPOSITION BASF SE (DE) 2024-08-07 EP disclosed
EP-4410100-A2 PLANT HEALTH COMPOSITION BASF SE (DE) 2024-08-07 EP disclosed
EP-4406412-A2 PLANT HEALTH COMPOSITION BASF SE (DE) 2024-07-31 EP disclosed
CN-111801014-B Fungicidal compositions of cloroxen 巴斯夫农业公司 2022-05-27 CN disclosed
CN-111801014-B Fungicidal compositions of cloroxen 巴斯夫农业公司 2022-05-27 CN disclosed
CN-111801014-A Fungicidal compositions of cloroxen 巴斯夫农业公司 2020-10-20 CN disclosed
US-20130156932-A1 Method of increasing the milk and/or meat quantity of silage-fed animals BASF SE (DE) 2013-06-20 US disclosed
EP-2565180-A2 ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Oscotec Inc. (KR) 2013-03-06 EP disclosed
US-20120149707-A1 ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME OSCOTEC INC. (KR) 2012-06-14 US disclosed
US-20110105579-A1 Plant Health Composition BASF SE (DE) 2011-05-05 US disclosed
US-20100272853-A1 Method of Increasing the Milk and/or Meat Quantity of Silage-Fed Animals BASF SE (DE) 2010-10-28 US disclosed
EP-2234481-A2 METHOD OF INCREASING THE MILK AND/OR MEET QUANTITY OF SILAGE-FED ANIMALS BASF SE (DE) 2010-10-06 EP disclosed
WO-2009080609-A2 METHOD OF INCREASING THE MILK AND/OR MEET QUANTITY OF SILAGE-FED ANIMALS BASF SE (DE) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149707-A1 ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME HIF1A, HIF1AN, EGLN3 SMN1; SMN2 3764/4885MEN1 4558/4885KMT2A 2186/4885
US-20110105579-A1 Plant Health Composition GET3, BROX, ATL3 SMN1; SMN2 2981/4885MEN1 338/4885KMT2A 3811/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.