Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554616 | 0.85 | HPGD (0.46) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL12051392 | 0.79 | HPGD (0.54) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL29324128 | 0.79 | CYP1A2 (0.51) | ALDH1A1KMT2AL3MBTL1GAAHSD17B10 | |
| SCHEMBL12051349 | 0.78 | HPGD (0.44) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL23561314 | 0.77 | HPGD (0.65) | HPGDALDH1A1KMT2AGAAHSD17B10 | |
| SCHEMBL4446634 | 0.77 | CA1 (0.56) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL12051336 | 0.76 | ALDH1A1 (0.52) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL12051389 | 0.76 | HPGD (0.56) | HPGDHDAC3HDAC1ALDH1A1KMT2A | |
| SCHEMBL14870983 | 0.75 | KMT2A (0.67) | HPGDALDH1A1KMT2AL3MBTL1GAA | |
| SCHEMBL29324219 | 0.75 | MAPT (0.41) | HPGDALDH1A1KMT2AL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015035003-A1 | THIOETHER PRODRUG COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-03-12 | — | — | WO | disclosed |
| WO-2015035003-A1 | THIOETHER PRODRUG COMPOSITIONS AS ANTI-HIV AND ANTI-RETROVIRAL AGENTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-03-12 | — | — | WO | disclosed |