Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556206 | 0.95 | MAPT (0.50) | MAPTTDP1L3MBTL1TNFKLF5 | |
| SCHEMBL498389 | 0.92 | MAPT (0.55) | MAPTTDP1L3MBTL1TNFKLF5 | |
| SCHEMBL16556032 | 0.85 | KMT2A (0.51) | MAPTTDP1L3MBTL1TNFKLF5 | |
| SCHEMBL29728510 | 0.84 | HTR1D (0.39) | L3MBTL1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL16555989 | 0.84 | NPSR1 (0.40) | MAPTL3MBTL1KLF5NPSR1KMT2A | |
| SCHEMBL15233894 | 0.84 | MAPT (0.47) | MAPTTDP1L3MBTL1NPSR1KMT2A | |
| SCHEMBL13273237 | 0.83 | TDP1 (0.49) | MAPTTDP1L3MBTL1TNFKLF5 | |
| SCHEMBL16556219 | 0.83 | MAPT (0.46) | MAPTTDP1L3MBTL1TNFKLF5 | |
| SCHEMBL16556171 | 0.82 | RARB (0.39) | NPSR1PRSS1ACR | |
| SCHEMBL16555956 | 0.82 | KMT2A (0.51) | MAPTTDP1L3MBTL1TNFKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044239-B9 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-08-28 | — | — | EP | disclosed |
| EP-3044239-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2019-03-27 | — | — | EP | disclosed |
| US-9481745-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2016-11-01 | — | — | US | disclosed |
| US-20160208027-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE ITALIA S.R.L. (IT) | 2016-07-21 | — | — | US | disclosed |
| EP-3044239-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015032939-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-03-12 | — | — | WO | disclosed |