SCHEMBL498389

SCHEMBL498389

Cc1cc(C(C)(C)C)cc(OC(=O)c2ccccc2)c1OC(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NPSR1 Q6W5P4 2/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
SLC6A3 Q01959 1/20 0.44
TNF P01375 1/20 0.43
KLF5 Q13887 1/20 0.43
NOD1 Q9Y239 1/20 0.43
ESR1 P03372 2/20 0.42
ESR2 Q92731 2/20 0.42
HSD17B10 Q99714 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
PKM P14618 1/20 0.41
LMNA P02545 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
MDM2 Q00987 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16555653 0.92 MAPT (0.50) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL16556206 0.92 MAPT (0.50) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL13273237 0.91 TDP1 (0.49) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL16555956 0.90 KMT2A (0.51) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL16556032 0.90 KMT2A (0.51) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL28681474 0.89 MAPT (0.45) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL15233894 0.88 MAPT (0.47) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL15234257 0.88 MAPT (0.47) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL498401 0.88 ESR1 (0.43) MAPTTDP1L3MBTL1NPSR1KMT2A
SCHEMBL25921367 0.87 KMT2A (0.51) MAPTTDP1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930869-A Auxiliary agent for olefin polymerization, olefin catalyst system, prepolymerized catalyst composition and olefin polymerization method 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119930872-A Catalyst system, prepolymerized catalyst composition and olefin polymerization process 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-119841986-A Propylene polymer and synthetic method thereof 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119841996-A Ethylene/propylene random polymer and synthetic method thereof 中国石油化工股份有限公司 2025-04-18 CN claimed
CN-119591770-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN claimed
CN-119591768-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN claimed
CN-119591771-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN claimed
CN-119591769-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2025-03-11 CN claimed
CN-115667321-B Method for producing catalyst for olefin polymerization, and method for producing olefin polymer 东邦钛株式会社 2024-09-17 CN claimed
CN-118108889-A Organic polymer carrier, Z-N catalyst, and preparation method and application thereof 中国石油天然气股份有限公司 2024-05-31 CN claimed
US-20100301059-A1 Thermoformed Article with High Stiffness and Good Optics W. R. GRACE & CO.-CONN. 2010-12-02 US claimed
US-20100197874-A1 Random Propylene Copolymer Compositions, Articles and Process W. R. GRACE & CO.-CONN. 2010-08-05 US claimed
WO-2010078512-A2 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO claimed
WO-2010078480-A1 PROPYLENE IMPACT COPOLYMER AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO claimed
US-20100173769-A1 Enhanced Procatalyst Composition and Process W. R. GRACE & CO.-CONN. 2010-07-08 US claimed
US-20100174105-A1 Production of Substituted Phenylene Aromatic Diesters W.R. GRACE & CO.-CONN. 2010-07-08 US claimed
WO-2010078485-A1 PROPYLENE-BASED POLYMER, ARTICLES, AND PROCESS FOR PRODUCING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO claimed
WO-2010078503-A1 ENHANCED PROCATALYST COMPOSITION AND PROCESS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO claimed
US-20100168342-A1 Propylene Impact Copolymer and Method W. R. GRACE & CO.-CONN. 2010-07-01 US claimed
US-20100168353-A1 Propylene-Based Polymer, Articles, and Process for Producing Same W.R. GRACE & CO.-CONN. 2010-07-01 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100174105-A1 Production of Substituted Phenylene Aromatic Diesters DDT, COMT, DDC MAPT 2278/4885TDP1 399/4885L3MBTL1 901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.