Hydrochloric Acid

Hydrochloric Acid

SCHEMBL16556002

CCCCCCCCCCCCCCCC[n+]1ccccc1CC.[Cl-]

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.46
CHRM1 known ✓ P11229 2/20 0.46
ACHE known ✓ P22303 2/20 0.46
SLC6A2 known ✓ P23975 2/20 0.46
SLC6A3 known ✓ Q01959 2/20 0.46
CHRM3 known ✓ P20309 1/20 0.44
SMN1; SMN2 Q16637 8/20 0.54
NPC1 O15118 6/20 0.54
RAB9A P51151 6/20 0.54
KMT2A Q03164 6/20 0.54
HTT P42858 6/20 0.54
MEN1 O00255 5/20 0.54
KDM4E B2RXH2 5/20 0.54
RAD52 P43351 4/20 0.54
MAPK1 P28482 3/20 0.54
NPSR1 Q6W5P4 3/20 0.54
LMNA P02545 3/20 0.54
HSP90AA1 P07900 2/20 0.54
RGS12 O14924 1/20 0.54
USP2 O75604 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30330307 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL30330728 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL28336788 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL30331714 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL30330632 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL30330981 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL11427007 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
Hydrochloric Acid SCHEMBL30331037 1.00 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AKMT2AHTT
SCHEMBL5134796 0.98 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AKMT2AHTT
SCHEMBL1396476 0.98 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968537-B2 Anti-dandruff compositions and hair care formulations containing zinc pyrithione and quaternary ammonium salt JUBILANT INGREVIA LIMITED (IN) 2018-05-15 US claimed
US-20160374914-A2 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT LIFE SCIENCES LTD (IN) 2016-12-29 US claimed
US-20160220468-A1 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT INGREVIA LIMITED (IN) 2016-08-04 US claimed
CN-105744836-A ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT 吉友联生命科学有限公司 2016-07-06 CN claimed
EP-3041356-B1 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT LIFE SCIENCES LTD (IN) 2020-12-16 EP disclosed
US-20190350200-A1 SYNERGISTIC ANTIMICROBIAL COMPOSITIONS JUBILANT LIFE SCIENCES LIMITED (IN) 2019-11-21 US disclosed
EP-3534708-A1 SYNERGISTIC ANTIMICROBIAL COMPOSITIONS Jubilant Life Sciences Limited (IN) 2019-09-11 EP disclosed
CN-110113942-A Synergistic antimicrobial compositions 朱比兰特生命科学有限公司 2019-08-09 CN disclosed
US-10314312-B2 Synergistic antimicrobial composition of zinc pyrithione JUBILANT LIFE SCIENCES LIMITED (IN) 2019-06-11 US disclosed
US-9968537-B2 Anti-dandruff compositions and hair care formulations containing zinc pyrithione and quaternary ammonium salt JUBILANT INGREVIA LIMITED (IN) 2018-05-15 US disclosed
US-20170208815-A1 SYNERGISTIC ANTIMICROBIAL COMPOSITION OF ZINC PYRITHIONE JUBILANT INGREVIA LIMITED (IN) 2017-07-27 US disclosed
US-20160374914-A2 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT LIFE SCIENCES LTD (IN) 2016-12-29 US disclosed
US-20160220468-A1 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT INGREVIA LIMITED (IN) 2016-08-04 US disclosed
EP-3041356-A1 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT Jubilant Life Sciences Limited (IN) 2016-07-13 EP disclosed
CN-105744836-A ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT 吉友联生命科学有限公司 2016-07-06 CN disclosed
WO-2015033351-A1 ANTI-DANDRUFF COMPOSITIONS AND HAIR CARE FORMULATIONS CONTAINING ZINC PYRITHIONE AND QUATERNARY AMMONIUM SALT JUBILANT LIFE SCIENCES LIMITED (IN) 2015-03-12 WO disclosed