SCHEMBL16556038

SCHEMBL16556038

Cc1cc(C(C)(C)C)cc(OC(=O)N(C(C)C)C(C)C)c1OC(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 3/20 0.39
LMNA P02545 1/20 0.39
MEN1 O00255 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
BCHE P06276 1/20 0.37
ALDH1A1 P00352 2/20 0.36
PKM P14618 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
TNF P01375 1/20 0.36
KLF5 Q13887 1/20 0.36
NOD1 Q9Y239 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16556107 0.95 MAPT (0.45) MAPTTDP1L3MBTL1KMT2ALMNA
SCHEMBL16555956 0.87 KMT2A (0.51) MAPTTDP1L3MBTL1KMT2ALMNA
SCHEMBL29728592 0.86 BCHE (0.38) KMT2AMEN1BCHEALDH1A1HDAC8
SCHEMBL498389 0.86 MAPT (0.55) MAPTTDP1L3MBTL1KMT2ALMNA
SCHEMBL16965699 0.86 BCHE (0.38) KMT2AMEN1BCHEALDH1A1HDAC8
SCHEMBL16556114 0.85 ABCB1 (0.37) NPSR1CA1CA2
SCHEMBL16555698 0.85 TDP1 (0.46) MAPTTDP1L3MBTL1KMT2ALMNA
SCHEMBL16555941 0.84 MAPT (0.45) MAPTTDP1L3MBTL1KMT2ALMNA
SCHEMBL16556216 0.83 PLK1 (0.37) MAPTNPSR1HDAC8
SCHEMBL16556032 0.82 KMT2A (0.51) MAPTTDP1L3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3044239-B9 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-08-28 EP disclosed
EP-3044239-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2019-03-27 EP disclosed
US-9481745-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2016-11-01 US disclosed
US-20160208027-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLYOLEFINE ITALIA S.R.L. (IT) 2016-07-21 US disclosed
EP-3044239-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2016-07-20 EP disclosed
WO-2015032939-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-03-12 WO disclosed