Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 20/20 | 1.00 |
| ▸ | VEGFA | P15692 | 5/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16560808 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL19872148 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560939 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL18036885 | 0.93 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560942 | 0.93 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL17671086 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16561002 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL22908835 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560917 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL19872392 | 0.89 | EPAS1 (0.79) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3043784-A1 | ARYL ETHERS AND USES THEREOF | Peloton Therapeutics, Inc. (US) | 2016-07-20 | — | — | EP | disclosed |
| WO-2015035223-A1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2015-03-12 | — | — | WO | disclosed |