Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 20/20 | 1.00 |
| ▸ | VEGFA | P15692 | 5/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17671086 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16561002 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560917 | 1.00 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560805 | 0.93 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL17671080 | 0.93 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560869 | 0.93 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16556243 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560939 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL19872148 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL16560808 | 0.90 | EPAS1 (1.00) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015764-A1 | METHODS OF REDUCING INFLAMMATION OF THE DIGESTIVE SYSTEM WITH INHIBITORS OF HIF-2- ALPHA | PELOTON THERAPEUTICS INC. (US) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015764-A1 | METHODS OF REDUCING INFLAMMATION OF THE DIGESTIVE SYSTEM WITH INHIBITORS OF HIF-2- ALPHA | HIF1AN, EGLN2, EGLN3 | EPAS1 30/4885VEGFA 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.