Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109719 | 1.00 | TSHR (0.41) | TSHREPHX2SHBG | |
| SCHEMBL11868153 | 0.88 | TSHR (0.47) | TSHREPHX2 | |
| SCHEMBL11510797 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL14319842 | 0.86 | TSHR (0.32) | TSHRSHBG | |
| SCHEMBL2556322 | 0.84 | HRH1 (0.34) | TSHR | |
| SCHEMBL289192 | 0.80 | — | — | |
| SCHEMBL29284892 | 0.80 | — | — | |
| SCHEMBL14634416 | 0.80 | SCN1A (0.36) | — | |
| SCHEMBL19992470 | 0.80 | TSHR (0.39) | TSHR | |
| SCHEMBL8166800 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438106-B1 | OLIGOMERS WITH DI-PHENYLETHYNYL ENDCAPS | BOEING CO (US) | 2015-03-11 | — | — | EP | disclosed |