SCHEMBL109719

SCHEMBL109719

OC1CCC(OC2CCC(O)CC2)CC1

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
EPHX2 P34913 1/20 0.33
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16557008 1.00 TSHR (0.41) TSHREPHX2SHBG
SCHEMBL11868153 0.88 TSHR (0.47) TSHREPHX2
SCHEMBL11510797 0.86 TSHR (0.32) TSHR
SCHEMBL14319842 0.86 TSHR (0.32) TSHRSHBG
SCHEMBL2556322 0.84 HRH1 (0.34) TSHR
SCHEMBL289192 0.80
SCHEMBL29284892 0.80
SCHEMBL14634416 0.80 SCN1A (0.36)
SCHEMBL19992470 0.80 TSHR (0.39) TSHR
SCHEMBL8166800 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120059155-A Polysiloxane polycarbonate, transparent flame-retardant scratch-resistant polycarbonate material, and preparation methods and applications thereof 中国石油化工股份有限公司 2025-05-30 CN claimed
US-6395823-B1 MELT MIXING WITH POLYESTER COMPRISING ISOCYANATE REACTIVE GROUP AND REINFORCING FIBER; HEAT RESISTANCE, DUCTILITY, NONHYDROLYZING EASTMAN CHEMICAL COMPANY 2002-05-28 US claimed
EP-1017743-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR ENHANCING SOLID STATE POLYMERIZATION RATES EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP claimed
EP-1017742-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR CHAIN EXTENSION AND REACTIVE EXTRUSION EASTMAN CHEMICAL COMPANY (US) 2000-07-12 EP claimed
WO-1999011710-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR CHAIN EXTENSION AND REACTIVE EXTRUSION EASTMAN CHEMICAL COMPANY (US) 1999-03-11 WO claimed
WO-1999011711-A1 THERMOPLASTIC POLYURETHANE ADDITIVES FOR ENHANCING SOLID STATE POLYMERIZATION RATES EASTMAN CHEMICAL COMPANY (US) 1999-03-11 WO claimed
US-4526921-A Acetal resin, low molecular weight polycarbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-07-02 US claimed
US-4477652-A Condensation polymers of cyclic diols with aldehydes or acetals of aldehydes PHILLIPS PETROLEUM COMPANY (US) 1984-10-16 US claimed
JP-10130380-A None JP disclosed
EP-4349881-B1 POLYESTER MATERIAL AND POLYESTER PRODUCT, AND PREPARATION METHODS THEREFOR AND USE THEREOF NINGBO INSTITUTE OF MATERIALS TECH & ENGINEERING CHINESE ACADEMY OF SCIENCES (CN) 2026-04-29 EP disclosed
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-03-10 US disclosed
CN-120059155-A Polysiloxane polycarbonate, transparent flame-retardant scratch-resistant polycarbonate material, and preparation methods and applications thereof 中国石油化工股份有限公司 2025-05-30 CN disclosed
US-12173178-B2 Polyfunctional hydrazide crosslinker PPG INDUSTRIES OHIO, INC. (US) 2024-12-24 US disclosed
US-20240117215-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2024-04-11 US disclosed
US-4526921-A Acetal resin, low molecular weight polycarbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-07-02 US disclosed
US-4477652-A Condensation polymers of cyclic diols with aldehydes or acetals of aldehydes PHILLIPS PETROLEUM COMPANY (US) 1984-10-16 US disclosed
US-4340716-A EPOXY RESINS AND HARDENERS ASAHI DENKA KOGYO K.K. (JP) 1982-07-20 US disclosed
US-4065433-A Process for the manufacture of polyaddition products containing imide groups CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4046777-A INTERMEDIATES FOR HEAT-RESISTANT POLYMERS CIBA-GEIGY CORPORATION (US) 1977-09-06 US disclosed
US-3950451-A COUPLED PRODUCT OF ALKYLPHENOL AND PHENOL-FORMALDEHYDE-DIAMINE CONDENSATE ASAHI DENKA KOGYO K.K. (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570870-B2 Curable compositions, abrasion-resistant articles, and method of thermoforming the same VCL, LBR, ACR TSHR 927/4885EPHX2 4401/4885SHBG 3437/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.