Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 5/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31435440 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL25409122 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL32686064 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL13977425 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1697956 | 0.75 | DAO (0.42) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL22777733 | 0.74 | BCL2L1 (0.46) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL29728017 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL4908387 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL1697883 | 0.71 | DAO (0.42) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16395791 | 0.71 | MEN1 (0.41) | MEN1KMT2AALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9255111-B2 | Parasiticidal dihydroisoxazole compounds | ELI LILLY AND COMPANY (US) | 2016-02-09 | — | — | US | disclosed |
| US-20150072993-A1 | Parasiticidal Dihydroisoxazole Compounds | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2015-03-12 | — | — | US | disclosed |
| US-20150072993-A1 | Parasiticidal Dihydroisoxazole Compounds | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150072993-A1 | Parasiticidal Dihydroisoxazole Compounds | DHODH, DDT, CYP51A1 | MEN1 3118/4885KMT2A 2269/4885ALDH1A1 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.