Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691626 | 0.86 | PARP1 (0.43) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL2709066 | 0.85 | ELANE (0.47) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL6104787 | 0.85 | ESR1 (0.43) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL2709776 | 0.83 | PRKD3 (0.40) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL9494183 | 0.83 | CD38 (0.44) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL31327745 | 0.82 | ENPP3 (0.48) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL28858276 | 0.82 | ENPP3 (0.48) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL2711485 | 0.82 | MAP4K4 (0.41) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL30351049 | 0.82 | ESR1 (0.42) | KCNH2ADORA2AADORA1CYP3A4ADORA3 | |
| SCHEMBL2709144 | 0.81 | TNKS (0.44) | ADORA2AKDM4ELMNATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136851-A | Preparation method and application of quinoline ester compound | 楚雄师范学院 | 2025-06-13 | — | — | CN | claimed |
| CN-117397690-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 兰州大学 | 2024-01-16 | — | — | CN | claimed |
| CN-116991036-A | Fluorine-silicon modified polyurethane photoresist and preparation method thereof | 常州大学 | 2023-11-03 | — | — | CN | claimed |
| CN-115197134-A | Preparation method and application of camphorsulfonate compounds | 南京林业大学 | 2022-10-18 | — | — | CN | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| CN-121609673-B | PDE4 inhibitor and preparation method and application thereof | WUYI UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-117397690-B | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 广西田园生化股份有限公司 | 2026-04-24 | — | — | CN | disclosed |
| CN-117397690-B | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 广西田园生化股份有限公司 | 2026-04-24 | — | — | CN | disclosed |
| CN-120136851-A | Preparation method and application of quinoline ester compound | 楚雄师范学院 | 2025-06-13 | — | — | CN | disclosed |
| CN-115197134-B | Preparation method and application of camphorsulfonate compounds | 南京林业大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-117397690-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 兰州大学 | 2024-01-16 | — | — | CN | disclosed |
| CN-117397690-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 兰州大学 | 2024-01-16 | — | — | CN | disclosed |
| EP-0049776-B1 | 4-QUINOLINE METHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF SUBSTANCES WITH A PHARMACOLOGICAL ACTIVITY | BASF Aktiengesellschaft (DE) | 1985-07-31 | — | — | EP | disclosed |
| EP-0049555-B1 | 2-TRIFLUOROMETHYL-4-HYDROXY-3 QUINOLINE-CARBOXYLIC-ACID DERIVATIVES AND THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1984-02-22 | — | — | EP | disclosed |
| US-4429130-A | Pyrid-2'-yl-2-trifluoromethyl quinol-4-ylmethanes | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-31 | — | — | US | disclosed |
| EP-0012639-B1 | QUINOLEIN-3-CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE IN MEDICINES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1983-09-07 | — | — | EP | disclosed |
| EP-0049776-A2 | 4-Quinoline methane derivatives, their preparation and their use in the preparation of substances with a pharmacological activity | BASF Aktiengesellschaft (DE) | 1982-04-21 | — | — | EP | disclosed |
| EP-0049555-A1 | 2-Trifluoromethyl-4-hydroxy-3 quinoline-carboxylic-acid derivatives and their preparation | ROUSSEL-UCLAF (FR) | 1982-04-14 | — | — | EP | disclosed |
| EP-0012639-A2 | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-25 | — | — | EP | disclosed |
| US-3953453-A | ANTIMALARIAL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-04-27 | — | — | US | disclosed |