Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 15/20 | 0.43 |
| ▸ | GRB2 | P62993 | 3/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16558260 | 1.00 | CTSD (0.43) | CTSDGRB2OXTR | |
| SCHEMBL18735829 | 1.00 | CTSD (0.43) | CTSDGRB2OXTR | |
| SCHEMBL18735662 | 0.94 | CTSD (0.43) | CTSDGRB2OXTR | |
| SCHEMBL16558253 | 0.94 | CTSD (0.43) | CTSDGRB2OXTR | |
| SCHEMBL18719718 | 0.93 | CTSD (0.47) | CTSDGRB2 | |
| SCHEMBL18719739 | 0.91 | CTSD (0.44) | CTSD | |
| SCHEMBL18735659 | 0.91 | CTSD (0.42) | CTSDGRB2OXTR | |
| SCHEMBL18719736 | 0.85 | CTSD (0.44) | CTSDGRB2 | |
| SCHEMBL16558245 | 0.82 | CTSD (0.32) | CTSDOXTR | |
| SCHEMBL18735644 | 0.82 | CTSD (0.32) | CTSDOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3041468-B1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2018-06-13 | — | — | EP | disclosed |
| US-20170101444-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2017-04-13 | — | — | US | disclosed |
| US-20170101444-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2017-04-13 | — | — | US | disclosed |
| US-20160113901-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2016-04-28 | — | — | US | disclosed |
| US-20160113901-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2016-04-28 | — | — | US | disclosed |
| US-9233940-B2 | Cyclic peptidomimetic compounds as immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2016-01-12 | — | — | US | disclosed |
| US-9233940-B2 | Cyclic peptidomimetic compounds as immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2016-01-12 | — | — | US | disclosed |
| US-20150073042-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-03-12 | — | — | US | disclosed |
| WO-2015033303-A1 | CYCLIC PEPTIDOMIMETIC COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-03-12 | — | — | WO | disclosed |
| US-20150073042-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160113901-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | CD274, PDCD1LG2, PDCD1 | CTSD 1311/4885GRB2 422/4885OXTR 3260/4885 |
| US-20150073042-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | CD274, PDCD1LG2, PDCD1 | CTSD 1311/4885GRB2 422/4885OXTR 3260/4885 |
| US-20170101444-A1 | Cyclic Peptidomimetic Compounds as Immunomodulators | CD274, PDCD1LG2, PDCD1 | CTSD 1311/4885GRB2 422/4885OXTR 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.