SCHEMBL1655827

SCHEMBL1655827

C=Cc1ccnc(C=C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
HDAC8 Q9BY41 3/20 0.38
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TSHR P16473 1/20 0.35
MAP3K14 Q99558 2/20 0.34
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503544 1.00 ALDH1A1 (0.39) ALDH1A1HDAC8TP53TDP1TSHR
SCHEMBL21327710 0.85 ALDH1A1 (0.35) ALDH1A1HDAC8TP53TDP1TSHR
SCHEMBL29163627 0.85 ALDH1A1 (0.35) ALDH1A1HDAC8TP53TDP1TSHR
SCHEMBL30786154 0.85 ALDH1A1 (0.34) ALDH1A1HDAC8TSHRMAP3K14CYP3A4
SCHEMBL27845898 0.81 HDAC8 (0.36) HDAC8MAP3K14CYP3A4CYP2D6PSEN1
SCHEMBL10767296 0.81 HDAC3 (0.33) ALDH1A1HDAC8TP53TDP1MEN1
SCHEMBL18036717 0.80 KDM4E (0.48) ALDH1A1HDAC8TSHRMEN1NPC1
SCHEMBL6883985 0.78 MEN1 (0.56) ALDH1A1HDAC8TSHRMEN1NPC1
SCHEMBL29625350 0.78 CCR1 (0.42) ALDH1A1HDAC8TP53TDP1TSHR
SCHEMBL16682444 0.78 CCR1 (0.42) ALDH1A1HDAC8TP53TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114324320-A Efficient and recyclable pH test paper and preparation method thereof 浙江正信石油科技有限公司 2022-04-12 CN claimed
CN-1796476-A Unsaturated polyester insulating lacquer in two constituents without solvent SHANGHAI INST OF ELECTRIC TOOL (CN) 2006-07-05 CN claimed
CN-1796429-A Solidifiable resin composition in single constituent SHANGHAI INST OF ELECTRIC TOOL (CN) 2006-07-05 CN claimed
EP-1165690-B1 CURABLE RESIN COMPOSITION, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GEN ELECTRIC (US) 2004-12-15 EP claimed
CN-1152921-C Curable resin composition, preparation thereof, and articles derived therefrom ͨ�õ�����˾ 2004-06-09 CN claimed
US-6521703-B2 Comprises unsaturated polyester, aromatic monomer, and capped polyarylene ether for reducing curing shrinkage GENERAL ELECTRIC COMPANY 2003-02-18 US claimed
CN-1364184-A Curable resin compositions, methods of making, and articles made therefrom GEN ELECTRIC (US) 2002-08-14 CN claimed
US-20020016420-A1 Curable resin composition, method for the preparation thereof, and articles derived therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-02-07 US claimed
EP-1165690-A1 CURABLE RESIN COMPOSITION, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2002-01-02 EP claimed
WO-2001053413-A1 CURABLE RESIN COMPOSITION, METHOD FOR THE PREPARATION THEREOF, AND ARTICLES DERIVED THEREFROM GENERAL ELECTRIC COMPANY (US) 2001-07-26 WO claimed
US-4680357-A ADHESIVES THE DOW CHEMICAL COMPANY (US) 1987-07-14 US claimed
US-12441823-B2 Resin composition for optical shaping KURARAY NORITAKE DENTAL INC. (JP) 2025-10-14 US disclosed
EP-3900693-B1 USE OF A RESIN COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2024-03-20 EP disclosed
US-20230200207-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-22 US disclosed
US-11538693-B2 Substrate processing method and substrate processing system TOKYO ELECTRON LIMITED (JP) 2022-12-27 US disclosed
EP-0248930-A1 Synergistically stabilized mixed form halogenated and/or interhalogenated resins for disinfecting water AMETEK, INC. PLYMOUTH PRODUCTS DIVISION (US) 1987-12-16 EP disclosed
US-4680357-A ADHESIVES THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed
US-4594392-A Copolymer containing polyvinylpyridine crosslinked with divinylbenzene AMETEK, INC. - PLYMOUTH PRODUCTS DIVISION (US) 1986-06-10 US disclosed
US-4072807-A OLEFIN DISPROPORTIONATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1978-02-07 US disclosed
US-3995095-A Modification of polymers by treatment with olefins PHILLIPS PETROLEUM COMPANY (US) 1976-11-30 US disclosed