Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468626 | 0.84 | MEN1 (0.61) | CHKAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12468686 | 0.76 | MEN1 (0.60) | MAPK1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL228900 | 0.75 | CHKA (0.71) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL1335735 | 0.75 | CHKA (0.71) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28573230 | 0.74 | CHKA (0.69) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL2873979 | 0.74 | CHKA (0.72) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL12468704 | 0.73 | POLB (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| Hydrochloric Acid SCHEMBL3882134 | 0.73 | CHKA (0.71) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL12468998 | 0.72 | POLB (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC6 | |
| SCHEMBL20210248 | 0.71 | CHKA (0.77) | CHKAALDH1A1KDM4EMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150072976-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | ARAVIVE BIOLOGICS, INC. | 2015-03-12 | — | — | US | disclosed |
| US-20150072976-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | ARAVIVE BIOLOGICS, INC. | 2015-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150072976-A1 | SUBSTITUTED BENZAMIDES AND THEIR USES | NISCH, BTD, NAAA | CHKA 1753/4885ALDH1A1 483/4885KDM4E 1575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.