Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559089 | 0.88 | DDB1 (0.40) | NPSR1LMNAESR1ESR2DDB1 | |
| SCHEMBL16559117 | 0.86 | MEN1 (0.38) | NPSR1LMNAESR1ESR2DDB1 | |
| SCHEMBL16559120 | 0.84 | PDK2 (0.40) | NPSR1LMNAESR1ESR2DDB1 | |
| SCHEMBL16559090 | 0.83 | DDB1 (0.42) | LMNAESR1ESR2DDB1CRBN | |
| SCHEMBL7053703 | 0.78 | ESR1 (0.56) | NPSR1LMNAESR1ESR2PDK2 | |
| SCHEMBL16559116 | 0.74 | PDK2 (0.41) | LMNADDB1CRBNPDK2MEN1 | |
| SCHEMBL19727254 | 0.74 | PDK2 (0.39) | NPSR1LMNADDB1CRBNPDK2 | |
| SCHEMBL19447686 | 0.73 | ALDH1A1 (0.46) | LMNAESR1ESR2PDK2KDM4E | |
| SCHEMBL16559093 | 0.72 | SMN1; SMN2 (0.39) | NPSR1LMNAESR1ESR2DDB1 | |
| SCHEMBL16559121 | 0.71 | MEN1 (0.39) | NPSR1LMNAESR1ESR2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170365785-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE SALT, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-20170365786-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYMER AND AT LEAST ONE METAL COMPLEX AND TO ELECTROLUMINESCENT DEVICES CONTAINING SAID COMPOSITIONS | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-9815940-B2 | Polymers containing substituted triarylamine units and electroluminescent devices containing said polymers | MERCK PATENT GMBH (DE) | 2017-11-14 | — | — | US | disclosed |
| US-20150069303-A1 | POLYMERS CONTAINING SUBSTITUTED TRIARYLAMINE UNITS AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS | MERCK PATENT GMBH (DE) | 2015-03-12 | — | — | US | disclosed |