Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094511 | 0.91 | TLR8 (0.71) | TLR8TLR7 | |
| SCHEMBL1238138 | 0.90 | TLR8 (0.69) | TLR8TLR7 | |
| SCHEMBL10325171 | 0.84 | TLR8 (0.60) | TLR8TLR7 | |
| SCHEMBL22790540 | 0.83 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL1802374 | 0.83 | TLR8 (0.73) | TLR8TLR7 | |
| SCHEMBL1237666 | 0.82 | TLR8 (0.72) | TLR8TLR7 | |
| SCHEMBL19642416 | 0.82 | TLR8 (1.00) | TLR8TLR7 | |
| SCHEMBL27950487 | 0.80 | TLR8 (0.50) | TLR8TLR7 | |
| SCHEMBL10324863 | 0.79 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL7511336 | 0.78 | TLR8 (0.54) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160331758-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. | 2016-11-17 | — | — | US | claimed |
| US-20130018042-A1 | Toll-Like Receptor Agonist Formulations and Their Use | VENTIRX PHARMACEUTICALS, INC. | 2013-01-17 | — | — | US | claimed |
| JP-2011529916-A | — | — | 2011-12-15 | — | — | JP | claimed |
| EP-2322510-A2 | 8-substituted benzoazepines as toll-like receptor modulators | Array Biopharma, Inc. (US) | 2011-05-18 | — | — | EP | claimed |
| EP-2313111-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | Ventirx Pharmaceuticals, Inc. (US) | 2011-04-27 | — | — | EP | claimed |
| WO-2010014913-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-02-04 | — | — | WO | claimed |
| US-20100029585-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. | 2010-02-04 | — | — | US | claimed |
| US-20080234251-A1 | 8-Substituted Benzoazepines as Toll-Like Receptor Modulators | ARRAY BIOPHARMA INC. (US) | 2008-09-25 | — | — | US | claimed |
| EP-1940797-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2008-07-09 | — | — | EP | claimed |
| WO-2007024612-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | ARRAY BIOPHARMA INC. (US) | 2007-03-01 | — | — | WO | claimed |
| US-20160331758-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. | 2016-11-17 | — | — | US | disclosed |
| EP-3081558-A1 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2016-10-19 | — | — | EP | disclosed |
| US-9216192-B2 | Toll-like receptor agonist formulations and their use | VENTIRX PHARMACEUTICALS, INC. (US) | 2015-12-22 | — | — | US | disclosed |
| EP-2313111-B1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS INC (US) | 2013-09-04 | — | — | EP | disclosed |
| US-20130018042-A1 | Toll-Like Receptor Agonist Formulations and Their Use | VENTIRX PHARMACEUTICALS, INC. | 2013-01-17 | — | — | US | disclosed |
| WO-2010014913-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| US-20100029585-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | VENTIRX PHARMACEUTICALS, INC. | 2010-02-04 | — | — | US | disclosed |
| US-20080234251-A1 | 8-Substituted Benzoazepines as Toll-Like Receptor Modulators | ARRAY BIOPHARMA INC. (US) | 2008-09-25 | — | — | US | disclosed |
| EP-1940797-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Array Biopharma, Inc. (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007024612-A2 | 8-SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | ARRAY BIOPHARMA INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018042-A1 | Toll-Like Receptor Agonist Formulations and Their Use | TLR8, TLR7, TLR1 | TLR8 1/4885TLR7 2/4885 |
| US-20080234251-A1 | 8-Substituted Benzoazepines as Toll-Like Receptor Modulators | TLR8, TLR7, TLR9 | TLR8 1/4885TLR7 2/4885 |
| US-20160331758-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | TLR8, TLR7, TLR1 | TLR8 1/4885TLR7 2/4885 |
| US-20100029585-A1 | TOLL-LIKE RECEPTOR AGONIST FORMULATIONS AND THEIR USE | TLR8, TLR7, TLR1 | TLR8 1/4885TLR7 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.