Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL16563074 | 0.85 | TSHR (0.61) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL66196 | 0.83 | LMNA (0.59) | LMNACA1CA2MMP1MMP2 | |
| Lithium Ion SCHEMBL16563178 | 0.83 | SNCA (0.46) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6114756 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6916646 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6909666 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6918593 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6914534 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6912742 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 | |
| SCHEMBL6914794 | 0.81 | LMNA (0.56) | LMNACA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9595737-B2 | Non-aqueous electrolyte and power storage device using same | UBE INDUSTRIES, LTD. (JP) | 2017-03-14 | — | — | US | disclosed |
| EP-2849272-B1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE INDUSTRIES (JP) | 2017-01-11 | — | — | EP | disclosed |
| US-20150125761-A1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE INDUSTRIES, LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| EP-2849272-A1 | NON-AQUEOUS ELECTROLYTE AND POWER STORAGE DEVICE USING SAME | UBE Industries, Ltd. (JP) | 2015-03-18 | — | — | EP | disclosed |