Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 18/20 | 0.85 |
| ▸ | FAAH | O00519 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144178 | 0.92 | MGLL (1.00) | MGLLFAAHHPGDS | |
| SCHEMBL16564522 | 0.89 | MGLL (0.85) | MGLLFAAHHPGD | |
| SCHEMBL146033 | 0.89 | MGLL (0.85) | MGLLFAAHHPGDHPGDS | |
| SCHEMBL16564473 | 0.87 | MGLL (0.81) | MGLLFAAHHPGDS | |
| SCHEMBL697821 | 0.86 | MGLL (0.85) | MGLLFAAH | |
| SCHEMBL16564542 | 0.85 | MGLL (0.62) | MGLLFAAHHPGDHPGDS | |
| SCHEMBL148745 | 0.82 | MGLL (0.74) | MGLLFAAH | |
| SCHEMBL14877205 | 0.80 | MGLL (0.67) | MGLLFAAHHPGD | |
| SCHEMBL10175226 | 0.80 | MGLL (0.67) | MGLLFAAHHPGD | |
| SCHEMBL14647928 | 0.80 | MGLL (0.81) | MGLLFAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611774-B1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-18 | — | — | EP | disclosed |