Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.53 |
| ▸ | CCRL2 | O00421 | 4/20 | 0.40 |
| ▸ | CCR2 | P41597 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16564435 | 0.85 | MGLL (0.53) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL16564486 | 0.81 | MGLL (0.57) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL16564472 | 0.81 | MGLL (0.49) | MGLLCCRL2CCR2KCNH2 | |
| SCHEMBL145402 | 0.81 | MGLL (0.60) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL148315 | 0.78 | MGLL (0.57) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL16564330 | 0.78 | MGLL (0.53) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL145001 | 0.78 | MGLL (0.57) | MGLLCCR2KCNH2FAAH | |
| SCHEMBL16564451 | 0.77 | MGLL (0.53) | MGLLCCRL2CCR2KCNH2FAAH | |
| SCHEMBL16564522 | 0.77 | MGLL (0.85) | MGLLCCR2KCNH2FAAH | |
| SCHEMBL16564386 | 0.76 | MGLL (0.61) | MGLLCCRL2CCR2KCNH2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611774-B1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-18 | — | — | EP | disclosed |