Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 6/20 | 0.82 |
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.82 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.82 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.82 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.82 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.82 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.82 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.82 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.82 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.82 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.82 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953827 | 0.92 | EPHA2 (0.78) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL190519 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL22871921 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL13811793 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25021694 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023044 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL5556804 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023120 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL1688735 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL16084677 | 0.90 | GPBAR1 (1.00) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1364645-A1 | Pharmaceutical combinations for topical use based on iron chelators, metalloprotease inhibitors and factor XIII for the treatment of lipodermatosclerosis and trophic lesions of the cutaneous tissues and muccous membranes | ZAMBONI, Paolo (IT) | 2003-11-26 | — | — | EP | claimed |
| WO-1992016200-A1 | THE USE OF HYDROXAMIC ACID DERIVATIVES TO INHIBIT VIRAL REPLICATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-10-01 | — | — | WO | claimed |
| US-20140234398-A1 | Dissolution of Arterial Plaque | ATHERONOVA OPERATIONS, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140148422-A1 | TREATMENT OF GLUCOSE INTOLERANCE | ATHERONOVA OPERATIONS, INC. (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140142071-A1 | REGRESSION OF ARTERIAL PLAQUE | ATHERONOVA OPERATIONS, INC. (US) | 2014-05-22 | — | — | US | disclosed |
| US-8697633-B2 | Dissolution of arterial plaque | ATHERONOVA OPERATIONS, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-20130029946-A1 | DISSOLUTION OF ARTERIAL PLAQUE | ATHERANOVA OPERATIONS, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-8304383-B2 | Atherosclerosis therapy ; circulation of emulsifiers; using bile salts, saponins or detergent surfactant; concurrent administering with statin | ATHERONOVA OPERATIONS, INC. (US) | 2012-11-06 | — | — | US | disclosed |
| EP-2485738-A2 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | Atheronova Operations, Inc. (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044523-A2 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | ATHERONOVA OPERATIONS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| US-20110086829-A1 | COMPOSITIONS AND METHODS FOR TREATING OBESITY | ATHERONOVA OPERATIONS, INC. | 2011-04-14 | — | — | US | disclosed |
| US-20030153531-A1 | Modified polysaccharides exhibiting altered biological recognition | THERAPURE BIOPHARMA INC. (CA) | 2003-08-14 | — | — | US | disclosed |
| US-6479468-B1 | Modified polysaccharides exhibiting altered biological recognition | BIOMEDICAL FRONTIERS, INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1037642-A1 | MODIFIED POLYSACCHARIDES EXHIBITING ALTERED BIOLOGICAL RECOGNITION | BIOMEDICAL FRONTIERS, INC. (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999029328-A1 | MODIFIED POLYSACCHARIDES EXHIBITING ALTERED BIOLOGICAL RECOGNITION | BIOMEDICAL FRONTIERS, INC. (US) | 1999-06-17 | — | — | WO | disclosed |
| WO-1999008996-A1 | METHOD OF REDUCING A SCHIFF BASE | BIOMEDICAL FRONTIERS, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| US-5847110-A | Method of reducing a schiff base | BIOMEDICAL FRONTIERS, INC. (US) | 1998-12-08 | — | — | US | disclosed |
| WO-1998020905-A2 | TREATMENT OF IRON OVERLOAD DISORDERS | BIOMEDICAL FRONTIERS, INC. (US) | 1998-05-22 | — | — | WO | disclosed |
| US-5646316-A | ANTIMETASTASIS AND ANTITUMOR AGENTS | OSTEOARTHRITIS SCIENCES, INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1992016200-A1 | THE USE OF HYDROXAMIC ACID DERIVATIVES TO INHIBIT VIRAL REPLICATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1992-10-01 | — | — | WO | disclosed |