Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 1.00 |
| ▸ | EPHA2 | P29317 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 2/20 | 1.00 |
| ▸ | AKR1B1 | P15121 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | EFNA1 | P20827 | 1/20 | 1.00 |
| ▸ | PSEN1 | P49768 | 1/20 | 1.00 |
| ▸ | PSEN2 | P49810 | 1/20 | 1.00 |
| ▸ | APH1B | Q8WW43 | 1/20 | 1.00 |
| ▸ | NCSTN | Q92542 | 1/20 | 1.00 |
| ▸ | APH1A | Q96BI3 | 1/20 | 1.00 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | VDR | P11473 | 4/20 | 0.74 |
| ▸ | CASP7 | P55210 | 3/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ursocholanic Acid SCHEMBL19313776 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL190519 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL16084677 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL13811793 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023120 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25023044 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL5556804 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL25021694 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL22871921 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 | |
| Ursocholanic Acid SCHEMBL18575999 | 1.00 | GPBAR1 (1.00) | GPBAR1EPHA2HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023213540-A1 | PROCESS FOR THE PREPARATION OF CHOLIC ACID DERIVATIVES | CHEMELECTIVA S.R.L. (IT) | 2023-11-09 | — | — | WO | disclosed |
| EP-2893922-B1 | Pharmaceutical formulations for the treatment of pulmonary arterial hypertension | HEART BIOTECH PHARMA LTD (GB) | 2021-07-14 | — | — | EP | disclosed |
| EP-3285875-B1 | METHODS FOR THE SYNTHESIS OF CERAGENINS | UNIV BRIGHAM YOUNG (US) | 2020-11-11 | — | — | EP | disclosed |
| US-10245244-B2 | Pharmaceutical formulations for the treatment of pulmonary arterial hypertension | HEART BIOTECH PHARMA LIMITED (GB) | 2019-04-02 | — | — | US | disclosed |
| US-9146467-B2 | Coating compositions | MERCK PATENT GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9146467-B2 | Coating compositions | MERCK PATENT GMBH (DE) | 2015-09-29 | — | — | US | disclosed |
| US-20150196516-A1 | PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION | HEART BIOTECH PHARMA LIMITED (GB) | 2015-07-16 | — | — | US | disclosed |
| EP-2893922-A1 | Pharmaceutical formulations for the treatment of pulmonary arterial hypertension | Heart Biotech Pharma Limited (GB) | 2015-07-15 | — | — | EP | disclosed |
| US-20130236833-A1 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-09-12 | — | — | US | disclosed |
| US-20130236833-A1 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-09-12 | — | — | US | disclosed |
| US-8455176-B2 | Coating composition | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8455176-B2 | Coating composition | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| WO-2012047495-A2 | METHODS FOR PREPARING SYNTHETIC BILE ACIDS AND COMPOSITIONS COMPRISING THE SAME | KYTHERA BIOPHARMACEUTICALS, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
| WO-2010055406-A2 | COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-20100119972-A1 | COATING COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20100119972-A1 | COATING COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| EP-1817325-B1 | SULFATED MOLECULAR UMBRELLAS CONTAINING 6-200 CHOLANIC ACID (DERIVATIVE) UNITS AS ANTI-HIV AND ANTI-HSV AGENTS | UNIV LEHIGH (US) | 2009-01-21 | — | — | EP | disclosed |
| US-20070232576-A1 | Sulfated molecular umbrellas as anti-HIV and anti-HSV agents | LEHIGH UNIVERSITY (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070232576-A1 | Sulfated molecular umbrellas as anti-HIV and anti-HSV agents | LEHIGH UNIVERSITY (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232576-A1 | Sulfated molecular umbrellas as anti-HIV and anti-HSV agents | RPL17, SSU72, RPL27A | GPBAR1 414/4885EPHA2 1382/4885HSD17B10 471/4885 |
| US-20100119972-A1 | COATING COMPOSITION | S100A9, CAPG, C5 | GPBAR1 1101/4885EPHA2 24/4885HSD17B10 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.