Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2212212 | 0.89 | TSHR (0.58) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL31518611 | 0.87 | TSHR (0.57) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL14574872 | 0.87 | TSHR (0.72) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL25219425 | 0.86 | CYP1A2 (0.56) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL8781550 | 0.84 | TSHR (0.55) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL22861877 | 0.84 | CYP1A2 (0.53) | SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL23014660 | 0.84 | TSHR (0.51) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL222372 | 0.83 | KCNA5 (0.61) | KDM4EHPGDALDH1A1POLBKMT2A | |
| SCHEMBL647703 | 0.83 | TSHR (0.82) | KDM4EHPGDMAPTALDH1A1TSHR | |
| SCHEMBL25225354 | 0.82 | ALDH1A1 (0.62) | KDM4EHPGDMAPTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183394-A1 | CATALYST FOR PROPYLENE POLYMERIZATION, CATALYST SYSTEM FOR PROPYLENE POLYMERIZATION, AND PREPARATION AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2023-06-15 | — | — | US | claimed |
| WO-2025085848-A1 | ANTIBACTERIAL COMPOUNDS | ARREPATH, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2025054132-A1 | ANTIBACTERIAL COMPOUNDS | ARREPATH, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| US-20230183394-A1 | CATALYST FOR PROPYLENE POLYMERIZATION, CATALYST SYSTEM FOR PROPYLENE POLYMERIZATION, AND PREPARATION AND USE THEREOF | PETROCHINA COMPANY LIMITED (CN) | 2023-06-15 | — | — | US | disclosed |
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | disclosed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | KDM4E 1259/4885HPGD 2609/4885MAPT 3391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.