Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.43 |
| ▸ | ULK1 | O75385 | 11/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16570757 | 0.93 | PTK2 (0.43) | PTK2PTK2BULK1STAT6SYK | |
| SCHEMBL16570339 | 0.79 | PTK2 (0.55) | PTK2PTK2BULK1STAT6SYK | |
| SCHEMBL16570750 | 0.78 | PTK2 (0.66) | PTK2PTK2BULK1TBK1 | |
| SCHEMBL16570904 | 0.77 | ULK1 (0.46) | PTK2PTK2BULK1STAT6SYK | |
| SCHEMBL16570151 | 0.76 | ULK1 (0.47) | PTK2PTK2BULK1STAT6 | |
| SCHEMBL16571156 | 0.76 | ULK1 (0.51) | PTK2PTK2BULK1STAT6 | |
| SCHEMBL16570623 | 0.76 | PTK2 (0.46) | PTK2PTK2BULK1STAT6SYK | |
| SCHEMBL16570440 | 0.76 | ULK1 (0.48) | PTK2PTK2BULK1STAT6SYK | |
| SCHEMBL16571159 | 0.75 | PTK2 (0.56) | PTK2PTK2BULK1SYKTBK1 | |
| SCHEMBL16570363 | 0.73 | PTK2 (0.51) | PTK2PTK2BULK1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2016-08-04 | — | — | US | claimed |
| WO-2015038417-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | ASANA BIOSCIENCES, LLC (US) | 2015-03-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222014-A1 | COMPOUNDS FOR REGULATING FAK AND/OR SRC PATHWAYS | SRC, PTK2, FYN | PTK2 2/4885PTK2B 13/4885ULK1 769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.