Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 6/20 | 0.69 |
| ▸ | HEXB | P07686 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.66 |
| ▸ | RAD52 | P43351 | 1/20 | 0.66 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HK1 | P19367 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560557 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL20893694 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL11455625 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL9625491 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL9625295 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL9625427 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL9627022 | 1.00 | HEXA (0.69) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL2363008 | 0.98 | HEXA (0.71) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL6278202 | 0.93 | HEXA (0.71) | HEXAHEXBCYP3A4NFKB1HSD17B10 | |
| SCHEMBL9625779 | 0.92 | HEXA (0.81) | HEXAHEXBCYP3A4NFKB1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110079773-A1 | Selectively Functionalized Rylene Imides and Diimides | NORTHWESTERN UNIVERSITY | 2011-04-07 | — | — | US | disclosed |
| US-20110079773-A1 | Selectively Functionalized Rylene Imides and Diimides | NORTHWESTERN UNIVERSITY | 2011-04-07 | — | — | US | disclosed |
| US-7192967-B1 | Cyclic imide-substituted pyridylalkane, alkene, alkine carboxamides useful as cytostatic and immunosuppressive agents | ASTELLAS PHARMA GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110079773-A1 | Selectively Functionalized Rylene Imides and Diimides | RAE1, RICTOR, RET | HEXA 4473/4885HEXB 4602/4885CYP3A4 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.