SCHEMBL2363008

SCHEMBL2363008

CCCCCN1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HEXA P06865 6/20 0.71
HEXB P07686 6/20 0.71
POLB P06746 2/20 0.68
NR1I2 O75469 1/20 0.68
AHR P35869 1/20 0.68
RAD52 P43351 1/20 0.68
RCE1 Q9Y256 1/20 0.68
CYP1B1 Q16678 1/20 0.67
CYP3A4 P08684 1/20 0.64
NFKB1 P19838 1/20 0.64
HSD17B10 Q99714 1/20 0.64
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
ALDH1A1 P00352 2/20 0.62
KDM4E B2RXH2 1/20 0.62
HPGD P15428 1/20 0.62
HK1 P19367 1/20 0.62
APEX1 P27695 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625491 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL9625295 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL20893694 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL11455625 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL9625427 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL9627022 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL14560557 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL1657181 0.98 HEXA (0.69) HEXAHEXBPOLBNR1I2AHR
SCHEMBL6278202 0.95 HEXA (0.71) HEXAHEXBPOLBNR1I2AHR
SCHEMBL9626265 0.91 HEXA (0.83) HEXAHEXBPOLBNR1I2AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118159296-A Automatic synthesis of polymeric double drugs 索尼集团公司 2024-06-07 CN claimed
CN-118043082-A Pyrrolobenzodiazepine conjugates for the treatment of cancer 索尼集团公司 2024-05-14 CN claimed
US-20240132725-A1 SPACING LINKER GROUP DESIGN FOR BRIGHTNESS ENHANCEMENT IN DIMERIC OR POLYMERIC DYES Sony Group Corporation (JP) 2024-04-25 US claimed
EP-4355754-A1 METHOD FOR PREPARING FLUOROPHORE- AND CHROMOPHORE-CONTAINING CONJUGATES FOR VISUAL DETECTION OF ANALYTE MOLECULES Sony Group Corporation (JP) 2024-04-24 EP claimed
US-11945955-B2 Polymeric tandem dyes with linker groups Sony Group Corporation (JP) 2024-04-02 US claimed
WO-2024062318-A1 POLYMERS WITH STEROIDS OR VITAMINS Sony Group Corporation (JP) 2024-03-28 WO claimed
WO-2024062319-A1 POLYMERS WITH DUAL THERAPEUTIC AGENTS Sony Group Corporation (JP) 2024-03-28 WO claimed
US-11939474-B2 Water soluble fluorescent or colored dyes and methods for their use Sony Group Corporation (JP) 2024-03-26 US claimed
EP-3294811-B1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY GROUP CORP (JP) 2024-02-28 EP claimed
CN-117460735-A Method for preparing conjugates containing fluorophores and chromophores for visual detection of analyte molecules 索尼集团公司 2024-01-26 CN claimed
US-8389745-B2 Phosphonate fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2013-03-05 US claimed
US-20120116079-A1 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES ELITECHGROUP MDX LLC 2012-05-10 US claimed
US-7767834-B2 Phosphonylated fluorescent dyes and conjugates ELITECH HOLDING B.V. (NL) 2010-08-03 US claimed
US-7671218-B2 Phosphonate fluorescent dyes and conjugates Elitech Holdings B.V. (NL) 2010-03-02 US claimed
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2008-08-28 US claimed
JP-2008510041-A 2008-04-03 JP claimed
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2007-07-26 US claimed
EP-1781675-A2 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES Epoch Biosciences, Inc. (US) 2007-05-09 EP claimed
US-20060199955-A1 Phosphonylated fluorescent dyes and conjugates EPOCH BIOSCIENCES, INC. (US) 2006-09-07 US claimed
WO-2006020947-A2 PHOSPHONATE FLUORESCENT DYES AND CONJUGATES EPOCH BIOSCIENCES, INC. (US) 2006-02-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11945955-B2 Polymeric tandem dyes with linker groups CHRM1, IK, TMT1A HEXA 2978/4885HEXB 3033/4885POLB 2515/4885
US-20080207887-A1 PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES PHOSPHO1, PFAS, PHPT1 HEXA 1059/4885HEXB 1226/4885POLB 2192/4885
US-20070172832-A1 Phosphonate fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 HEXA 828/4885HEXB 936/4885POLB 1521/4885
US-20060199955-A1 Phosphonylated fluorescent dyes and conjugates PHOSPHO1, PFAS, PHPT1 HEXA 1059/4885HEXB 1226/4885POLB 2192/4885
US-11939474-B2 Water soluble fluorescent or colored dyes and methods for their use CHRM1, CHRM2, IK HEXA 1595/4885HEXB 1754/4885POLB 3027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.