Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 19/20 | 0.75 |
| ▸ | AR | P10275 | 19/20 | 0.75 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998925 | 1.00 | PGR (0.75) | PGRARNR3C2LMNA | |
| SCHEMBL12998936 | 0.91 | PGR (0.62) | PGRARNR3C2LMNA | |
| SCHEMBL13768715 | 0.90 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL13796418 | 0.90 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL16572811 | 0.90 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL12942947 | 0.90 | AR (0.75) | PGRARNR3C2 | |
| SCHEMBL13556634 | 0.89 | PGR (0.78) | PGRARNR3C2 | |
| SCHEMBL12943049 | 0.89 | PGR (0.78) | PGRARNR3C2 | |
| SCHEMBL14949842 | 0.89 | PGR (0.59) | PGRARNR3C2LMNA | |
| SCHEMBL16572798 | 0.86 | AR (0.76) | PGRARNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238149-B1 | 19-NOR-STEROID DERIVATIVES WITH A 15ALPHA, 16ALPHA-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER IP GMBH (DE) | 2015-03-18 | — | — | EP | disclosed |