Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559863 | 0.91 | ELANE (0.33) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL16559839 | 0.88 | ELANE (0.40) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL16844797 | 0.87 | ELANE (0.38) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL16844799 | 0.87 | ELANE (0.38) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL16351988 | 0.86 | ELANE (0.47) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL21101841 | 0.85 | ELANE (0.50) | ELANEBACE1KMT2AATMMAPT | |
| SCHEMBL19159458 | 0.84 | BACE1 (0.38) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL18358976 | 0.84 | ELANE (0.37) | ELANEHTTPOLBAPEX1TDP1 | |
| SCHEMBL17433313 | 0.84 | ELANE (0.49) | ELANETDP1BACE1KMT2AATM | |
| SCHEMBL15338965 | 0.83 | BACE1 (0.49) | ELANEPOLBBACE1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2848676-B1 | Liquid crystal medium | MERCK PATENT GMBH (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2848676-A2 | Liquid crystal medium | Merck Patent GmbH (DE) | 2015-03-18 | — | — | EP | disclosed |